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The antibodies in the sera of 160 tuberculous persons and in a control group of 100 healthy persons were investigated by Middlebrook-Dubos (M-D), Boyden hemagglutination and modified M-D antiglobulin methods. By the M-D method 88% of the sera from 135 persons with lung tuberculosis, and 57.1% sera from 21 persons with other organ tuberculosis gave positive results.

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Sera of patients with pulmonary and extrapulmonary tuberculosis, of blood donors and cattle sera were researched in hemagglutination reaction, using untreated and papain-treated sheep erythrocytes, and in hemolysis reaction. 58% of patients with pulmonary tuberculosis and 23% of normal sera, reacted positive in at least one of the 3 reactions. 24 sera of 44 patients with extrapulmonary tuberculosis were found to be positive.

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