Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Proteolytic enzymes and wound debridement: a literature review.
Wounds
November 2024
Department of Pharmacy, National and Kapodistrian University of Athens School of Health Sciences: Ethniko kai Kapodistriako Panepistemio Athenon, Zografou, Greece.
Background: Wound debridement is crucial for effective wound management and essential for removing necrotic tissue, reducing bacterial load, and encouraging granulation. While surgical debridement is prevalent, it can be traumatic and can potentially delay healing by enlarging the wound area.
Objective: To summarize the existing literature on the role of proteolytic enzymes in wound debridement, with a focus on their applications, benefits, limitations, and future potential in wound care management.
Diacerein reduces inflammasome activation and SARS-CoV-2 virus replication: a proof-of-concept translational study.
Front Pharmacol
October 2024
Laboratory of Vascular Biology and Atherosclerosis (Aterolab), State University of Campinas (UNICAMP), Campinas, Brazil.
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is linked to high mortality, primarily through an intense inflammatory response. Diacerein has emerged as a potential therapy for COVID-19 due to its potential impact in decreasing the inflammasome activation and coronavirus replication. This study aims to explore diacerein's influence in inhibiting both viral replication and the inflammatory response after SARS-CoV-2 infection.
View Article and Find Full Text PDFDiagnosis, treatment, and prognosis of adult pancreatoblastoma.
Cancer Med
August 2024
The First Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, China.
Background: Pancreatoblastoma (PB) is one of the rare malignant tumors that typically occurs in children. Cases of PB in adults are highly unusual. This disease often presents with subtle symptoms and lacks characteristic clinical manifestations, leading to diagnostic challenges.
View Article and Find Full Text PDFComparison of the Efficacy of Corticosteroids With Enzymatic Agents in the Postoperative Sequelae for Lower Third Molar Surgery: A Prospective Study.
Cureus
March 2024
Oral and Maxillofacial Surgery, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.
Article Synopsis
- The study investigates the effectiveness of different treatments—corticosteroids and natural enzymatic agents—on post-surgical recovery after the removal of impacted lower third molars, focusing on pain, swelling, and trismus.
- A total of 150 patients were divided into three groups, receiving either prednisolone, a combination of natural enzymes, or serratiopeptidase, alongside standard pain relief medication.
- The primary aim was to compare swelling levels between the groups, while secondary objectives included measuring differences in postoperative pain and trismus, utilizing statistical tests to analyze the data collected on the first and seventh days after surgery.
Decreased Proteasomal Function Exacerbates Endoplasmic Reticulum Stress-Induced Chronic Inflammation in Obese Adipose Tissue.
Am J Pathol
June 2024
Department of Pathology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan; Department of Surgical Pathology, Hokkaido University Hospital, Sapporo, Japan. Electronic address:
Low-grade chronic inflammation contributes to both aging and the pathogenesis of age-related diseases. White adipose tissue (WAT) in obese individuals exhibits chronic inflammation, which is associated with obesity-related disorders. Aging exacerbates obesity-related inflammation in WAT; however, the molecular mechanisms underlying chronic inflammation and its exacerbation by aging remain unclear.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!