Corpus luteum activity was monitored in 15 women undergoing nonsurgical management of ectopic pregnancy with local methotrexate injection followed by alternating oral methotrexate and citrovorum factor (group A, n = 8) or local methotrexate injection alone (group B, n = 7). All patients initially demonstrated a viable corpus luteum (plasma progesterone ranged from 1.4 to 19 ng/ml). The treatment was successful in 14, with the exception of one whose tube ruptured 11 days after local administration of methotrexate, despite a continuous decrease in beta human chorionic gonadotropin, 17 beta-estradiol and plasma progesterone levels. There seems to be no correlation between the success of the treatment and the behavior of beta human chorionic gonadotropin, 17 beta-estradiol and plasma progesterone. Three patients from group A and two from group B displayed an initial rise in beta human chorionic gonadotropin following the initiation of the therapy, but the corpus luteum response differed. In group B patients, 17 beta-estradiol and plasma progesterone levels increased in parallel with beta human chorionic gonadotropin. Group A patients displayed a continuous decrease in 17 beta-estradiol and plasma progesterone levels despite the elevation of beta human chorionic gonadotropin, suggesting a possible effect of the systemic methotrexate on corpus luteum activity.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1159/000294872 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Impact of luteal blood perfusion and expression of estrus on pregnancy rates of Bos taurus embryo recipients exposed to fixed-time embryo transfer.
Anim Reprod Sci
January 2025
University of Georgia, Department of Animal and Dairy Sciences, Athens, GA 30602, USA. Electronic address:
This study evaluated the impact of luteal blood perfusion (BP) and expression of estrus on pregnancy rates of Bos taurus embryo recipients exposed to fixed-timed embryo transfer (FTET) using a gonadotropin-releasing hormone (GnRH)- and progesterone-based ovulation synchronization protocol. Postpartum beef cows (n = 746) were exposed to a GnRH/progesterone-based ovulation synchronization protocol. Luteal morphometry and BP were assessed using color Doppler ultrasonography 9 days after CIDR removal concurrently with FTET.
View Article and Find Full Text PDFRelative increase in walking activity in lactating dairy cows submitted to timed artificial insemination: Risk factors and subsequent fertility.
Anim Reprod Sci
January 2025
Agrotecnio Center, Department of Animal Sciences, University of Lleida, Lleida 25198, Spain.
The objectives of this study were: (i) to evaluate the associations between postpartum health disorders, relative increase in walking activity (RIWA) and expression of behavioral estrus intensity captured by pedometers; (ii) to assess associations between RIWA and pregnancy in cows submitted to timed artificial insemination (TAI). Lactating dairy cows (n = 881) were enrolled in the study. Cows were submitted to a 5d TAI protocol with insertion of a progesterone device.
View Article and Find Full Text PDFRelationships between activity monitoring device data and ovarian, uterine, hormonal, and pregnancy variables in beef cows.
Theriogenology
January 2025
Department of Animal Sciences, University of Florida, Gainesville, FL, USA. Electronic address:
Implementing accelerometer technologies in beef operations is an alternative to increase precision in estrous detection. We hypothesized that (1) the accelerometer algorithm has similar accuracy in detecting behavioral estrus as does visual observation of pressure-sensitive sensors (estrus patches) in grazing beef cows; (2) variables measured by the accelerometer, such as estrus intensity, are associated with hormonal, ovarian, and uterine variables monitored before, during, and after estrus; and (3) the accelerometer variables are associated with the probability of pregnancy in grazing beef cows submitted to embryo transfer (ET). Fifty cows were fitted with accelerometer and patches to detect estrus after a synchronization protocol in eight subsequent rounds.
View Article and Find Full Text PDFMassive haemoperitoneum from an unidentified source in a woman with vWD.
BMJ Case Rep
January 2025
Obstetrics and Gynecology, All India Institute of Medical Sciences, New Delhi, India.
Von Willebrand's disease (vWD) is an inherited coagulopathy. In women, this condition can present as periovulatory intra-abdominal bleeding or bleeding from the corpus luteum. A diagnosed case of vWD presented as an emergency with nausea, acute abdominal pain and dizziness.
View Article and Find Full Text PDFFollicular growth, ovulation, and pregnancy responses to PGF-indued luteolysis and spontaneous return to estrus in Standardbred mares with large diestrous follicles.
J Equine Vet Sci
January 2025
Equine Fertility Group, Faculty of Veterinary Medicine, Universidad Cardenal Herrera-CEU, CEU Universities, 46115 Alfara del Patriarca, Valencia, Spain; Broline International AB, 51293 Svenljunga, Sweden. Electronic address:
The objective of this study was to compare the fertility of diestrous mares with a follicle ≥ 30 mm in diameter treated with prostaglandin F2α (PGF) (PGF group) or left untreated for 7 days (SP group). Standardbred mares (n = 46) were assigned randomly to the SP (n = 23) and PGF groups (n = 23) when they were identified with a corpus luteum (CL) of unknown age and a follicle ≥ 30 mm in diameter (Day 0). The most frequent outcome in the PGF group was estrus and ovulation of the dominant follicle (74 %), while the outcomes of the SP mares 7 days after Day 0 were more variable: estrus and follicle regression (30 %), diestrous ovulation (22 %) and diestrus along with follicle regression (26 %) of the dominant follicles.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!