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Cardiotoxicity Associated With a Low Doses of 5-FU Promotes Morphoquantitative Changes in the Intrinsic Cardiac Nervous System.
Cardiovasc Toxicol
January 2025
Department of Morphological Sciences, State University of Maringa, Maringa, Parana, Brazil.
5-Fluorouracil (5-FU) is a chemotherapeutic that is used to treat solid tumors. However, 5-FU is associated with several side effects, including cardiotoxicity. Considering the importance of the intrinsic cardiac nervous system (ICNS) for the heart and that little is known about effects of 5-FU on this nervous system plexus, the purpose of the present study was to evaluate effects 5-FU at a low dose on the ICNS and oxidative and inflammatory effects in the heart in Wistar rats.
View Article and Find Full Text PDFMorphological, Physiological, and Transcriptional Changes in L. Under In Vitro Polyethylene Glycol-Induced Water Stress.
Biology (Basel)
January 2025
Division of Biotechnology, CSIR-Institute of Himalayan Bioresource Technology, Palampur 176061, Himachal Pradesh, India.
Saffron ( L.), a perennial geophyte from the Iridaceae family, blooms in autumn and thrives in Mediterranean-like climates. It is highly valued for its therapeutic and commercial uses.
View Article and Find Full Text PDFExploring Innovative Approaches for the Analysis of Micro- and Nanoplastics: Breakthroughs in (Bio)Sensing Techniques.
Biosensors (Basel)
January 2025
Universidad Autónoma de Nuevo León, Facultad de Ciencias Químicas, Av. Universidad S/N Ciudad Universitaria, San Nicolás de los Garza 66455, Nuevo León, Mexico.
Plastic pollution, particularly from microplastics (MPs) and nanoplastics (NPs), has become a critical environmental and health concern due to their widespread distribution, persistence, and potential toxicity. MPs and NPs originate from primary sources, such as cosmetic microspheres or synthetic fibers, and secondary fragmentation of larger plastics through environmental degradation. These particles, typically less than 5 mm, are found globally, from deep seabeds to human tissues, and are known to adsorb and release harmful pollutants, exacerbating ecological and health risks.
View Article and Find Full Text PDFsp. nov., sp. nov. and four other endophytes associated with aquatic plants from Sri Lanka and their extracellular enzymatic potential.
Front Cell Infect Microbiol
January 2025
Center for Yunnan Plateau Biological Resources Protection and Utilization, Qujing Normal University, Qujing, Yunnan, China.
Endophytic fungi associated with selected aquatic plants, and were evaluated. sp. nov.
View Article and Find Full Text PDFCellulase from for biofuel application: enzymatic characterization and inhibition tolerance investigation.
Prep Biochem Biotechnol
January 2025
Department of Biotechnology, Kalasalingam Academy of Research and Education, Krishnankovil, Tamil Nadu, India.
Halophilic bacteria are promising candidates for biofuel production because of their efficient cellulose degradation. Their cellulases exhibit high activity, even in the presence of inhibitors and under extreme conditions, making them ideal for biorefinery applications. In this study, we isolated a strain of (Kadal6) from decomposed cotton cloth on a Rameshwaram seashore.
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