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To report a rare case of severe oligoasthenoteratozoospermia which seems to be associated with long-term topical povidone-iodine (PVP-I) therapy. A 45-year-old man with secondary infertility was diagnosed with mild asthenospermia before undergoing in vitro fertilization (IVF). A repeat sperm analysis (SA) on June 30, 2022, after three months of using compound PVP-I liniment to treat fungal infection under a fingernail and toenail, revealed severe oligoasthenoteratozoospermia.
View Article and Find Full Text PDFEffect of a Topical Antibiotic and Povidone-Iodine Versus Povidone Iodine Alone on Conjunctival Flora: A Systematic Review and Meta-Analysis.
J Cataract Refract Surg
February 2025
Bolton NHS Foundation Trust, Bolton, UK.
Topic: This systematic review and meta-analysis aimed to determine whether adding preoperative topical antibiotics to povidone-iodine (PVI) offers any additional benefit over PVI alone in reducing conjunctival bacterial flora, thereby potentially lowering the risk of postoperative endophthalmitis. The participants included 1423 eyes undergoing elective intraocular surgeries (e.g.
View Article and Find Full Text PDFReducing Rates of Endophthalmitis from Intravitreal Injections - strategies and areas of controversy.
Curr Opin Ophthalmol
February 2025
Mid Atlantic Retina, The Retina Service of Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Purpose Of Review: Post-injection endophthalmitis (PIE) is the most concerning complication that accompanies intravitreal injections. This review discusses the recent literature in endophthalmitis prophylaxis including types of antisepsis, the use of topical antibiotics, methods of anesthesia, masking, and office-based versus operating room-based injections.
Recent Findings: Povidone iodine (PI) remains the gold standard for PIE prophylaxis.
Double Povidone-Iodine 5% Preparation Before Cataract Surgery for Endophthalmitis Prevention.
Eye Contact Lens
January 2025
UPMC Eye Center (J.L.O., L.Z., A.M., E.G.R., R.M.Q.S., D.K.D.), University of Pittsburgh School of Medicine, Pittsburgh, PA; Charles T. Campbell Laboratory of Ophthalmic Microbiology (A.M., E.G.R., R.M.Q.S., D.K.D.), Department of Ophthalmology, University of Pittsburgh, Pittsburgh, PA; Associated Retina Consultants (J.L.O.), Phoenix, AZ; and San Antonio Eye Center (J.W.), San Antonio, TX.
Objective: To compare endophthalmitis rates after cataract extraction in patients with different preoperative prophylaxis: double povidone-iodine preparation with topical antibiotics versus a control group.
Methods: All cases of postoperative endophthalmitis over the last 17 years were reviewed. Incidence rates of endophthalmitis for all cataract surgeries (current procedural terminology codes 66982 and 66984) performed by 26 surgeons were calculated.
The use of topical antiseptic solutions in the healing process of post-surgical skin wounds in dogs (Canis lupus familiaris).
Acta Cir Bras
January 2025
Universidade Federal Rural de Pernambuco - Programa de Pós-Graduação em Medicina Veterinária - Departamento de Morfologia e Fisiologia Animal - Recife (PE) - Brazil.
Purpose: To evaluate whether the effectiveness of topical antiseptic solutions in restoring skin continuity solutions is related to their antimicrobial action or to their action in maintaining moisture, in dogs undergoing elective surgeries.
Methods: Forty dogs, 20 males and 20 females, underwent orchiectomy and oophorectomy, respectively. Thereafter, the animals were allocated into four groups (n = 5) and treated with different topical solutions: polyhexanide 0.
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