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Behçet syndrome in children and adults: discovering similarities and differences by a comparative study.
Rheumatology (Oxford)
February 2023
Rheumatology Unit, Meyer Children's University Hospital, and NEUROFARBA Department.
Objective: Behçet's syndrome (BS) is a rare disorder with a relapsing-remitting course. Clinical variance across geographical regions and different age groups has been observed. This study matched the demographic, clinical and treatment features of adult- and juvenile-onset BS in the Italian population.
View Article and Find Full Text PDFIntroduction: Behcet's disease (BD) is a multi-systemic disorder with muco-cutaneous, ocular, arthritic, vascular or central nervous system involvement. The role of γδ T cells is implicated in BD. The activation status of γδ T cells and their cytokine secretion against phosphoantigens are evaluated in BD.
View Article and Find Full Text PDFThe role of streptococcal hypersensitivity in the pathogenesis of Behçet's Disease.
Eur J Dermatol
December 2008
Institute of Dermato-Immunology and -Allergy, Southern TOHOKU Research Institute for Neuroscience, Koriyama, Fukushima, Japan.
Behçet's disease (BD) is still considered as a mysterious multisystemic disorder characterized by recurrent involvement of muco-cutaneous, ocular, intestinal, vascular and/or nervous system organs. In this review, we would like to highlight and discuss several important advances in our understanding of the pathogenesis of BD based on the intrinsic genetic factors including HLA-B51 and MICA expression and extrinsic triggering factors. As one of the extrinsic triggering factors, we focused on the hypersensitivity against oral streptococci which might be acquired through the innate immune mechanism.
View Article and Find Full Text PDF[Autochthonous Behçet's disease. Apropos of 73 cases].
Rev Rhum Mal Osteoartic
April 1989
Service de Rhumatologie, Hôpital de la Conception, Marseille.
A multicenter study of Behçet's disease in France confirms the male predominance (62 p. cent), the mean age of onset in the 4th decade, the frequent muco-cutaneous, ocular, articular manifestations (94 p. cent), the skin hypersensitivity (68 p.
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