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Magnetic resonance imaging evidence of "silent" cerebrovascular toxicity in cocaine dependence.
Biol Psychiatry
May 1999
Psychiatry Service, Little Rock VA Medical Center, Arkansas 72114, USA.
Background: Cocaine and its metabolites can produce vasospasm. Cocaine-dependent (CD) patients are at increased risk for stroke, and a high frequency of brain perfusion defects has been observed in clinically asymptomatic CD subjects. This is the first controlled magnetic resonance imaging (MRI) study of clinically asymptomatic CD subjects.
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