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Microsurgery
June 2007
Department of Microsurgery, Centro Médico Nacional "20 de Noviembre", I.S.S.S.T.E., Mexico City, Mexico.
Progenitor cell transplantation has been considered as a potential angiogenesis therapy for the ischemic hindlimb. In this work we performed an ischemic hindlimb model in dogs. We ligated the middle sacra and the external right iliac arteries.
View Article and Find Full Text PDFJ Vasc Surg
February 2005
Department of Vascular Surgery, Yale University School of Medicine, New Haven, CT 06510, USA.
Artificial blood vessels composed of viable tissue represent the ideal vascular graft. Compliance, lack of thrombogenicity, and resistance to infections as well as the ability to heal, remodel, contract, and secrete normal blood vessel products are theoretical advantages of such grafts. Three basic elements are generally required for the construction of an artificial vessel: a structural scaffold, made either of collagen or a biodegradable polymer; vascular cells, and a nurturing environment.
View Article and Find Full Text PDFFront Biosci
May 2004
Centre for Research in Vascular Biology, University of Queensland, Brisbane, QLD 4072, Australia.
The inadequacy of conventional synthetic grafts has led to efforts to construct a superior vascular graft. In vivo tissue engineering is one approach to this problem that has been investigated for half a century and enables the construction of autogenous vascular prostheses. Three types of in vivo engineering are explored: remodelling of implanted scaffolds, fibrocollagenous tubes, and the artificial artery generated in the peritoneal cavity.
View Article and Find Full Text PDFJ Biomed Mater Res
February 1986
Urokinase (UK) was immobilized to the lumen of dacron-reinforced fibrocollagenous tubes (UK-FCT) using a glutaraldehyde entrapment process, in an effort to develop a fibrinolytic small diameter (i.e., 4 mm i.
View Article and Find Full Text PDFDacron-reinforced fibrocollagenous tubes (FCT) were synthesized from canine mongrels using the mandril-rod technique in order to develop a small diameter (i.e., 4 mm i.
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