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Ugeskr Laeger
October 2024
Afdelingen for Hud- og Kønssygdomme, Aarhus Universitetshospital.
Article Synopsis
- - Majocchi's granuloma is a rare fungal skin condition caused mainly by the fungus Trichophyton rubrum and is often linked to the use of topical steroids and weakened immune systems.
- - Symptoms typically include a rash with nodules, pustules, and scaling around hair follicles, which can be diagnosed through clinical exams and lab tests.
- - Treatment involves using systemic terbinafine along with topical antifungal medications for effective management.
Histopathologic Comparisons of Discoid Lupus Erythematosus and Folliculotropic Mycosis Fungoides in a Series of 43 Cases.
J Cutan Pathol
February 2025
Oakland University William Beaumont School of Medicine, Rochester Hills, Michigan, USA.
Background: Folliculotropic mycosis fungoides (FMF) is a rare cutaneous malignancy that can be mistaken for inflammatory diseases, such as discoid lupus erythematosus (DLE), due to the variability of histopathological findings.
Methods: This study aims to provide dermatopathologists with evidence-based histopathologic criteria to distinguish DLE from FMF by reporting overlapping and distinguishing microscopic features. Forty-three biopsies from patients with a confirmed diagnosis of DLE or FMF were graded for the presence or absence of 18 histopathologic features.
Extensive folliculitis and abscesses with a sporotrichoid distribution in a parenteral drug user.
J Infect Chemother
January 2025
Infectious Diseases Department, Consorcio Hospital General Universitario de Valencia, Spain.
We present the case of a 53-year-old Caucasian man with a history of intravenous drug use who presented with fever and multiple pustules predominantly affecting hairy areas of the body, with no clinical improvement despite previous antibiotic treatment. Culture of the pustules confirmed Candida albicans infection and histological examination of skin biopsies revealed suppurative granulomas compatible with candidomycetic folliculitis. The patient was successfully treated with systemic antifungals and discharged with resolution of symptoms.
View Article and Find Full Text PDFMajocchi's Granuloma - The Great Mimicker: A Case Report.
Case Rep Dermatol
October 2023
Skin Clinic, Kolding, Denmark.
Article Synopsis
- Fungal infections, often mistaken for conditions like eczema or psoriasis, can be difficult to identify and might be improperly treated with topical corticosteroids, leading to a condition called tinea incognita.
- A 54-year-old man experienced a painful rash in the genitoinguinal area that was initially treated unsuccessfully with various topical antifungals and antibiotics.
- Ultimately diagnosed with Majocchi's granuloma after thorough examination and histopathology, the patient successfully improved with a 16-week course of itraconazole, highlighting the need for awareness of such infections among non-specialist doctors.
Majocchi's granuloma-A multicenter retrospective cohort study.
JAAD Int
December 2023
Division of Public Health, Infectious Diseases, and Occupational Medicine, Mayo Clinic, Rochester, Minnesota.
Article Synopsis
- - Majocchi's granuloma (MG) is a rare fungal infection predominantly affecting hair follicles, often linked to previous use of immunosuppressants and corticosteroids, with case data coming from past reports due to its uncommon nature.
- - A study analyzed 147 adult patients over 30 years, revealing a median patient age of 55.6 years, with most patients being male, and Trichophyton species identified as the primary cause of MG.
- - Treatment typically involved a median duration of 31.5 days, primarily using oral terbinafine, leading to a successful clinical resolution in 96.6% of patients, although accurate diagnosis usually requires histopathologic confirmation.
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