Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/0030-4220(60)90295-4 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Multiple Subpial Transection for the Treatment of Landau-Kleffner Syndrome-Review of the Literature.
J Clin Med
December 2024
Department of Correct, Clinical and Imaging Anatomy, Medical University of Lublin, ul. Jaczewskiego 4, 20-090 Lublin, Poland.
As speech-related symptoms of Landau-Kleffner syndrome (LKS) are often refractory to pharmacotherapy, and resective surgery is rarely available due to the involvement of the vital cortex, multiple subpial transection (MST) was suggested to improve patient outcome and preserve cortical functions. Here, we analyze the reports about MST use in LKS, regarding its impact on seizures, language, behavior, EEG, cognition, and reported adverse effects. In conditions like LKS, surgery is not a popular treatment option and presumably should be considered sooner.
View Article and Find Full Text PDFThe Role of GABA Receptors in Anesthesia and Sedation: An Updated Review.
CNS Drugs
January 2025
Department of Anesthesiology, Jefferson Surgical Center Endoscopy, Sidney Kimmel Medical College, Jefferson Health, 111 S 11th Street, #7132, Philadelphia, PA, 19107, USA.
GABA (γ-aminobutyric acid) receptors are constituents of many inhibitory synapses within the central nervous system. They are formed by 5 subunits out of 19 various subunits: α1-6, β1-3, γ1-3, δ, ε, θ, π, and ρ1-3. Two main subtypes of GABA receptors have been identified, namely GABAA and GABAB.
View Article and Find Full Text PDFMethohexital-induced seizure during Wada test: A case report and alternative evaluation with etomidate.
Epileptic Disord
December 2024
Department of Neurology, LSU Health Shreveport, Shreveport, Louisiana, USA.
Reducing Respiratory Complications During Electroconvulsive Therapy (ECT) With Smaller Doses of Succinylcholine in a Morbidly Obese Patient: A Case Report.
Cureus
July 2024
Department of Psychiatry, University of Florida College of Medicine, Gainesville, USA.
Article Synopsis
- Anesthesia for electroconvulsive therapy (ECT) involves careful medication selection, including an induction agent and a neuromuscular blocker for muscle relaxation.
- A morbidly obese woman had severe hypoxic episodes during ECT due to bronchospasms caused by too high a dose of succinylcholine (SCh).
- Reducing the SCh dose to half improved the situation, leading to smoother treatments and preventing further episodes of hypoxia by allowing faster recovery of spontaneous breathing.
Ni/Cu Dual-Catalyzed Propargylation for the Stereodivergent Synthesis of Methohexital.
Adv Sci (Weinh)
September 2024
Hefei National Research Center for Physical Sciences at the Microscale and Department of Chemistry, University of Science and Technology of China, Hefei, 230026, China.
The development of efficient methodologies for the controlled manufacture of specific stereoisomers bearing quaternary stereocenters has prompted advances in a variety of scientific disciplines including pharmaceutical chemistry, materials science, and chemical biology. However, complete control of the absolute and relative stereochemical configurations of alkyne derivatives remains an unmet synthetic challenge. Herein, a Ni/Cu dual-catalyzed asymmetric propargylic substitution reaction is presented to produce propargylated products with all-carbon quaternary stereocenters in high yields with significant diastereo- and enantioselectivities (up to >20:1 dr, >99% ee).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!