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The association between early maladaptive schemas and romantic relationship satisfaction.
Front Psychol
December 2024
Department of Psychiatry, University of Debrecen Medical Center, Debrecen, Hungary.
Introduction: Relationship dynamics could be shaped by schemas, and relationship satisfaction could be depend on how couples perceive each other through these schemas. The main aim of this study was to assess how early maladaptive schemas are related to relationship satisfaction for both males and females in a relationship, by highlighting factors that contribute to relationship satisfaction, with a particular focus on the interaction of schemas between males and females.
Methods: The study involved a total of healthy 47 different-gender couples.
Lung immune incompetency after mild peritoneal sepsis and its partial restoration by type 1 interferon: a mouse model study.
Intensive Care Med Exp
December 2024
Department of Anesthesiology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-Ku, Tokyo, 113-0033, Japan.
Background: Sepsis is commonly associated with acute respiratory distress syndrome (ARDS). Although the exaggerated inflammation may damage intact lung tissues, a percentage of patients with ARDS are reportedly immunocompromised, with worse outcomes. Herein, using a murine sepsis model, time-course immune reprogramming after sepsis was evaluated to explore whether the host is immunocompromised.
View Article and Find Full Text PDFPeople who stutter are at a greater risk for developing symptoms of social anxiety, with up to 22-60% of adults who stutter meeting the criteria for a clinical diagnosis. Negative attitudes and feelings about speaking and stuttering are reported to emerge as early as the preschool years and are suspected to be due to exposure to negative listener reactions, stereotyping and social isolation. Repeated negative experiences lead to feelings of fear, embarrassment and loss of control during speaking which over time, leads to the development of more severe difficulties with speaking and an overall apprehension to speak as they perceive themselves as an incompetent communicator.
View Article and Find Full Text PDFCirculating mitochondria carrying cGAS promote endothelial Secreted group IIA phospholipase A2-mediated neuroinflammation through activating astroglial/microglial Integrin-alphavbeta3 in subfornical organ to augment central sympathetic overdrive in heart failure rats.
Int Immunopharmacol
January 2025
Department of Cardiac Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China; Shanghai Institute of Cardiovascular Diseases, Shanghai 200032, China. Electronic address:
Background: Sympathoexcitation, a manifestation of heart-brain axis dysregulation, contributes to the progression of heart failure (HF). Our recent study revealed that circulating mitochondria (C-Mito), a newly identified mediator of multi-organ communication, promote sympathoexcitation in HF by aggravating endothelial cell (EC)-derived neuroinflammation in the subfornical organ (SFO), the cardiovascular autonomic neural center. The precise molecular mechanism by which C-Mito promotes SFO-induced endothelial neuroinflammation has not been fully elucidated.
View Article and Find Full Text PDFPOST-MEASLES ACUTE VELOPHARYNGEAL INCOMPETENCE: A RARE CASE REPORT AND REVIEW OF LITERATURE.
West Afr J Med
November 2024
Paediatric Infectious Diseases Unit, Department of Paediatrics, Jos University Teaching Hospital/University of Jos, Jos, Plateau State, Nigeria.
Summary/introduction: Velopharyngeal incompetence(VPI) is the failure of closure of the velopharyngeal sphincter, which consists of the muscles of the soft palate and the superior pharyngeal constrictor, and functions to separate the nasopharynx and oropharynx during phonation and swallowing. VPI is most frequently congenital/syndromic (with structural deficit) but can be acquired. A subset of acquired VPI, occurring in structurally intact velopharynx, has been described in children, and these are isolated and acute-onset, with a substantial proportion thought to have an infectious origin.
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