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Papillary Muscles of the Left Ventricle: Integrating Electrical and Mechanical Dynamics.
J Cardiovasc Dev Dis
December 2024
Niculae Stancioiu Heart Institute, University of Medicine and Pharmacy "Iuliu Hatieganu", 400001 Cluj-Napoca, Romania.
Background: Papillary muscles are structures integrated into the mitral valve apparatus, having both electrical and mechanical roles. The importance of the papillary muscles (PM) is mainly related to cardiac arrhythmias and mitral regurgitation. The aim of this review is to offer an overview of the anatomy and physiology of the papillary muscles, along with their involvement in cardiovascular pathologies, including arrhythmia development in various conditions and their contribution to secondary mitral regurgitation.
View Article and Find Full Text PDFUtilization of ultrasonic aspirator for combined aortic and mitral valve decalcification: a case study.
J Cardiothorac Surg
January 2025
Department of Cardiothoracic Surgery, Mayo Clinic, Jacksonville, FL, USA.
Mitral and aortic annular calcification is an age-related degenerative process that can result in severe mitral and/or aortic stenosis and/or regurgitation. Annular calcification not only increases the surgical complexity but also increases the risk of complications. In this case report, we present the innovative use of the Sonopet ultrasonic surgical aspirator for aortic and mitral annular decalcification in a patient with hypertrophic obstructive cardiomyopathy, mild aortic stenosis and moderate mitral regurgitation in the presence of mitral annular calcification (MAC) and aorto-mitral curtain calcification.
View Article and Find Full Text PDFLab-on-paper for molecular testing with USB-powered isothermal amplification and fluidic control.
Mikrochim Acta
January 2025
Department of Biotechnology and Bioengineering, Chonnam National University, Gwangju, 61186, Republic of Korea.
The global healthcare market increasingly demands affordable molecular diagnostics for field testing. To address this need, we introduce a lab-on-paper (LOP) platform that integrates isothermal amplification with a specially designed paper strip for molecular testing through an automated microfluidics process. The LOP system is engineered for rapid, cost-effective, and highly sensitive detection, using USB-powered thermal management and a wax valve mechanism.
View Article and Find Full Text PDFBackground: Significant tricuspid regurgitation (TR) is associated with increased morbidity and mortality. The development of transcatheter valve repair therapies has opened a wide range of opportunities for treatment of patients with high surgical risk. Real-world data might improve patient selection and outcome.
View Article and Find Full Text PDFMagnetic Bistable Dome Actuators for Soft Robotics with High Volume Capacity and Motion Stability.
ACS Appl Mater Interfaces
January 2025
Institute of Humanoid Robots, Department of Precision Machinery and Precision Instrumentation, University of Science and Technology of China, Hefei 230026, P.R. China.
Magneto-responsive soft actuators hold significant promise in soft robotics due to their rapid responsiveness and untethered operation. However, controlling their deformations presents challenges because of their inherent flexibility and high degrees of freedom. Here, we present a magnetically driven bistable dome-shaped soft actuator that simplifies deformation by limiting it to two distinct states.
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