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Central venous pressure waveform analysis during sleep/rest: a novel approach to enhance intensive care unit post-extubation monitoring of extubation failure.
J Clin Monit Comput
October 2024
Biomedical Engineering Laboratory, Escola Politécnica, University of São Paulo (USP), São Paulo, Brazil.
This pilot study aimed to investigate the relation between cardio-respiratory parameters derived from Central Venous Pressure (CVP) waveform and Extubation Failure (EF) in mechanically ventilated ICU patients during post-extubation period. This study also proposes a new methodology for analysing these parameters during rest/sleep periods to try to improve the identification of EF. We conducted a prospective observational study, computing CVP-derived parameters including breathing effort, spectral analyses, and entropy in twenty critically ill patients post-extubation.
View Article and Find Full Text PDFFactors Associated With Change in S3-NIV Score Over Time in People With Chronic Respiratory Failure Treated With Long-Term Home Noninvasive Ventilation.
Arch Bronconeumol
August 2024
AGIR à dom, Homecare Charity, Meylan 38240, France. Electronic address:
Introduction: Monitoring changes in symptoms over time during long-term nocturnal home non-invasive ventilation (NIV) using patient-reported outcome measures is crucial. This study aimed to identify factors associated with changes in the S3-NIV total score, its two domains ("respiratory symptoms" and "sleep and NIV-related side effects") and individual item responses.
Methods: We conducted a retrospective, longitudinal data analysis of a cohort of adults with chronic respiratory failure treated with NIV.
Use of point-of-care ultrasound (POCUS) to monitor neonatal and pediatric extracorporeal life support.
Eur J Pediatr
April 2024
Pediatric Intensive Care Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Article Synopsis
- ECMO is an invasive life support technique that uses a blood pump and artificial lung to oxygenate blood for patients suffering from severe heart or lung failure, first used in 1975 for neonatal respiratory issues.
- Over the years, ECMO usage expanded but faced challenges in neonatal cases due to new therapies, while pediatric cases continued to grow steadily.
- Point-of-care ultrasound (POCUS) plays a crucial role in monitoring ECMO patients throughout treatment, from assessing candidacy to managing complications, highlighting the need for better guidelines in its application during ECMO support.
Exercise Stress Echocardiography of the Right Ventricle and Pulmonary Circulation.
J Am Coll Cardiol
November 2023
Institute of Clinical Physiology, National Research Council, Pisa, Italy. Electronic address:
Article Synopsis
- Exercise echocardiography is vital for evaluating the right ventricle and pulmonary circulation, but there's a need for clearer understanding of normal ranges and disease-specific variations.
- The study involved 2,228 participants including healthy individuals, athletes, and patients with different heart and lung conditions, who underwent echocardiography at rest and during exercise.
- Key findings indicate that certain measurements can predict increased mortality risk, highlighting significant differences in responses to exercise between healthy subjects and various patient groups.
Monitoring and Management of Respiratory Function in Pompe Disease: Current Perspectives.
Ther Clin Risk Manag
September 2023
Division of Pulmonary and Sleep Medicine, Department of Pediatrics, Duke University Medical Center, Durham, NC, USA.
Pompe disease (PD) is a neuromuscular disorder caused by a deficiency of acid alpha-glucosidase (GAA) - a lysosomal enzyme responsible for hydrolyzing glycogen. GAA deficiency leads to accumulation of glycogen in lysosomes, causing cellular disruption. The severity of PD is directly related to the extent of GAA deficiency - if no or minimal GAA is produced, symptoms are severe and manifest in infancy, known as infantile onset PD (IOPD).
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