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http://dx.doi.org/10.1161/01.cir.23.4.562 | DOI Listing |
Inflamm Bowel Dis
January 2025
Graduate Program in Basic and Applied Immunology, Biochemistry and Immunology Department, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo 14040-902, Brazil.
Background: Colorectal cancer (CRC) remains a significant cause of morbidity and mortality worldwide. In patients with inflammatory bowel disease, who have twice the risk of developing CRC, chronic inflammation has been recognized to contribute to colitis-associated cancer (CAC) development. Jacalin, a lectin extracted from jackfruit seeds, has been shown to recognize altered glycosylation and to exert antiproliferative and cytotoxic effects in CRC.
View Article and Find Full Text PDFFront Med (Lausanne)
December 2024
Department of Orthopedics, The Second People's Hospital of Hefei, Hefei Hospital Affiliated to Anhui Medical University, Hefei, Anhui, China.
Background: The link between waist-to-height ratio (WHtR) and osteoporosis (OP) remains a contentious issue in the field of medical research. Currently, the available evidence on this association is deemed insufficient. This topic has garnered significant attention and is a focal point of ongoing investigations.
View Article and Find Full Text PDFMikrochim Acta
December 2024
College of Chemistry and Chemical Engineering, Yan'an University, Yan'an, 716000, Shaanxi, China.
A nanocomposite consisting of gold nanoparticles (AuNPs), poly(diallyldimethylammonium chloride) (PDDA), and reduced graphene oxide (rGO) was fabricated by a two-step chemical reduction method. Firstly, a PDDA-rGO composite was prepared by using hydrazine hydrate as a reducing agent. Subsequently, the AuNP-PDDA-rGO composite was prepared in ethylene glycol with PDDA-rGO and HAuCl as raw materials using sodium citrate as a reduction agent.
View Article and Find Full Text PDFKaohsiung J Med Sci
December 2024
Department of Gastrointestinal Surgery, The Second Affiliated Hospital of Soochow University, Suzhou, China.
This study aimed to investigate whether activation of PPARγ regulates M1/M2 macrophage polarization to attenuate dextran sulfate sodium salt (DSS)-induced inflammatory bowel disease (IBD) via the STAT-1/STAT-6 pathway in vivo and in vitro. We first examined the effect of PPARγ on macrophage polarization in LPS/IFN-γ-treated M1 RAW264.7 cells and IL-4/IL-13-treated M2 RAW264.
View Article and Find Full Text PDFChemosphere
December 2024
Department of Environmental Research, Korea Institute of Civil Engineering and Building Technology, Gorang-Daero 283, Ilsanseo-Gu, Goyang, Gyeonggi, 10223, Republic of Korea; Department of Civil and Environment Engineering, University of Science and Technology (UST), 217 Gajeong-Ro, Yuseong-Gu, Daejeon, 34113, Republic of Korea. Electronic address:
Gravity-driven membrane (GDM) systems are increasingly recognized as sustainable and energy-efficient solutions for decentralized water treatment. However, membrane fouling, particularly by organic matter, remains a significant operational challenge, necessitating regular chemical cleaning to maintain performance. The present study was undertaken to investigate the cleaning efficiency of sodium dichloroisocyanurate (NaDCC) tablets, a novel solid-state alternative to conventional liquid cleaning agents such as sodium hypochlorite (NaOCl), sodium lauryl sulfate (SLS), acetic acid, and citric acid.
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