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Antibiotic exposure is associated with minimal gut microbiome perturbations in healthy term infants.
Microbiome
January 2025
Division of Gastroenterology, Hepatology, and Nutrition, The Children's Hospital of Philadelphia, Philadelphia, PA, 19146, USA.
Background: The evolving infant gut microbiome influences host immune development and later health outcomes. Early antibiotic exposure could impact microbiome development and contribute to poor outcomes. Here, we use a prospective longitudinal birth cohort of n = 323 healthy term African American children to determine the association between antibiotic exposure and the gut microbiome through shotgun metagenomics sequencing as well as bile acid profiles through liquid chromatography-mass spectrometry.
View Article and Find Full Text PDFVerification of an alteration in the gut microbiota that increases nutritional risk in patients on hemodialysis.
Biosci Microbiota Food Health
July 2024
Department of Gastroenterological and Transplant Surgery, Graduate School of Biomedical and Health Science, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551, Japan.
In end-stage kidney disease requiring hemodialysis, patients at nutritional risk have a poor prognosis. The gut microbiota is important for maintaining the nutritional status of patients. However, it remains unclear whether an altered gut microbiota correlates with increased nutritional risk in patients undergoing hemodialysis.
View Article and Find Full Text PDFEvaluation of MENAQUINONE-7 and fat-soluble vitamin production by starter cultures during fermentation in dairy products using RPLC method.
Food Sci Nutr
November 2024
Department of Food Engineering, Engineering Faculty Suleyman Demirel University Isparta Turkey.
Vitamin K2, also known as menaquinone, has become a significant research focus, particularly in fermented products. This study aims to investigate the content of menaquinone-7 (MK-7), an essential form of vitamin K, and other fat-soluble vitamins (A, D, E) during the fermentation of various fermented milk products. The vitamin contents of six fermented milk products were analyzed: two yogurt samples (produced with commercial starter and probiotic starter), two kefir samples (produced with commercial starter and kefir grain), and milk fermented with or .
View Article and Find Full Text PDFOsteopontin associated Bifidobacterium bifidum microencapsulation modulates infant fecal fermentation and gut microbiota development.
Food Res Int
December 2024
South China University of Technology, School of Food Science and Engineering, Overseas Expertise Introduction Center for Discipline Innovation of Food Nutrition and Human Health, Guangzhou 510640, China; Sino-Singapore International Research Institute, Guangzhou 510555, China. Electronic address:
Probiotic supplementation is an effective method for improving infant gut health, and probiotic encapsulation can enhance probiotic viability under adverse environmental conditions while ensuring an adequate amount of probiotic is delivered to the target site to confer a health benefit for the host. In this study, Bifidobacterium bifidum R0071 was microencapsulated using pectin or alginate, combined bovine milk osteopontin (OPN) as an excipient during the microencapsulation process. The microencapsulated probiotics were subjected to in vitro simulated infant gastrointestinal digestion and a fecal fermentation model to assess survival capacity and their impact on gas and organic acid production, as well as the development of gut microbiota.
View Article and Find Full Text PDFGrape pomace high-methoxyl pectin: A new prebiotic stabilizer for low-fat synbiotic yogurt gels - Optimization and characterization.
Int J Biol Macromol
December 2024
Institute of Materials Science, Faculty of Engineering, Kiel University, 24143 Kiel, Germany. Electronic address:
High-methoxyl pectin (HMP, 72.5 % esterification degree and galacturonic acid content of 67.9 %) was extracted from grape pomace using a sequential ultrasound-microwave extraction.
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