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Antioxidant influence on poultry liver morphology and hepatocyte ultrastructure.
Vet World
November 2019
Department of Veterinary Medicine, Federal State Budget Educational Institution of Higher Education "Penza State Agrarian University," Penza, Russia.
Background And Aim: The poultry farming development is held back by necessity to use the concentrates with the increased number of crude protein, mycotoxicoses, and subclinical infections concentration. They make a significant impact on the liver, therefore affecting its morphofunctional condition. Antioxidants use can prevent the negative influence of these factors.
View Article and Find Full Text PDFStudies on the chemical identity and biological functions of pangamic acid.
Arzneimittelforschung
April 1999
Lehrstuhl für Phytopathologie, Labor für Angewandte Biochemie, Technische Universität München, Freising-Weihenstephan, Germany.
Pangamic acid (6-O-(dimethylaminoacetyl)-D-gluconic acid) has been detected 1938 and described as a natural, universally occurring substance with multiple biological and medical functions. In this respect pangamic acid has been worldwide on the market since decades as a drug stimulating cellular respiration. In addition to the natural pangamic acid, diisopropylammonium dichloroacetate (DIPA), a synthetic product not found in biological material, is on the market requesting similar biological functions.
View Article and Find Full Text PDFExamination of toxicity of diisopropylammonium dichloracetate (DADA), remedies for cardiac diseases, toward isolated rat hepatocytes.
Meikai Daigaku Shigaku Zasshi
April 1992
Department of Internal Medicine, Meikai University School of Dentistry, Saitama, Japan.
Oxygen uptake (OU) and cell viability (CV) of isolated rat hepatocytes as a part of the indexes of hepatopathy were determined following treatment with DADA, the active principle of pangamic acid. DADA increased OU at high concentrations, but not at low ones. However, CV became higher as the concentration became lower.
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