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[Anesthesia for laparoscopic surgery].

Ther Umsch

August 1993

Département d'Anesthésie Réanimation, Centre hospitalier régional, France.

A thorough understanding of the physiological repercussions of the pneumoperitoneum is essential in order ot properly grasp the safety rules governing anesthesia for laparoscopic surgery. As a general rule systemic vascular resistance increases as the heart flow rate and venous return circulation decrease. Variations in the ventilation/perfusion ratio explain the origin of hypercapnia observed in patients.

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Motor axons can form sprouts from their terminal arborizations in response to partial denervation, and when exposed to pharmacological blocking agents like TTX, botulinum toxins alpha-bungarotoxin, or curare. Each of these experimental procedures has cessation of muscle contractile activity as a common feature. We tested the specific role of muscle fiber inactivity in regulating nerve terminal sprouting by chronically treating adult frog (Rana pipiens) cutaneous pectoris muscles with formamide.

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