[Trichomalacia and trichotillomania].

Arch Klin Exp Dermatol

Published: November 1998

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Introduction: Trichotillomania (TTM) is characterized by patchy alopecia of hair bearing areas. This is because of compulsive urge to pull the hair. Scalp is the most common site for pulling hair.

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Article Synopsis
  • - A 43-year-old man showed signs of patchy hair loss and re-growth patterns typical of trichotillomania, prompting a biopsy for diagnosis.
  • - The biopsy results showed abnormalities associated with trichotillomania, including a unique feature where hair shafts appeared split and contained certain materials, resembling a "hamburger in a bun."
  • - This "hamburger bun sign" is a new observation that could help in identifying traumatic injuries in biopsy examinations related to trichotillomania.
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Background: Trichotillomania (TM) is a chronic disorder in which patients traumatically remove their own hair in a bizarre pattern. TM histopathological findings are not well defined.

Methods: Twenty-eight scalp biopsies of TM were reviewed.

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Trichotillomania (TTM) is an impulse disorder, in which patients chronically pull hair from the scalp and/or other sites. Very early onset of hair pulling in children under the age of 6 may be more benign and self-limiting than the more common syndrome of late childhood onset hair pulling. While far more women and adolescent girls appear for treatment, survey studies suggest chronic hair pulling also occurs in males.

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Ten patients with traumatic alopecia (trichotillomania) were being investigated histologically and, in five of them, hairs from the affected scalp area were plucked out for direct microscopic examination. Some histologic features appear to be specific markers for traumatic alopecia: empty hair ducts, plucked out hair bulbs, clefts in hair matrix, catagen involution of empty outer root sheaths, Miescher's trichomalacia in the deep dermis and torn-off sebaceous glands. Other signs are unspecific, such as presence of catagen and anagen VI hairs, infundibular plugging, melanin in keratin plugs and in the dermal papilla.

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