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Beyond the Score: Exploring the Associations Between Adverse Childhood Experiences and Electrophysiological Responses to Errors.
Stress Health
February 2025
Psychology Department, Mount St. Vincent University, Halifax, Canada.
Adverse childhood experiences (ACEs) have diverse effects on physical development and mental health. This study aimed to clarify the relationship between the quantity of ACE exposure, type of ACE exposure, and subjective level of stress felt, correlated with event-related potential activity across the scalp, while controlling for relevant confounding variables. Fifty-three participants aged 18-32 years completed questionnaires assessing their current mental health, self-regulation, childhood socioeconomic status, and history of traumatic events.
View Article and Find Full Text PDFDoes fragmented sleep mediate the relationship between deficits in sleep spindles and memory consolidation in schizophrenia?
Sleep Adv
December 2024
Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Study Objectives: Sleep spindles, defining electroencephalographic oscillations of nonrapid eye movement (NREM) stage 2 sleep (N2), mediate sleep-dependent memory consolidation (SDMC). Spindles are also thought to protect sleep continuity by suppressing thalamocortical sensory relay. Schizophrenia is characterized by spindle deficits and a correlated reduction of SDMC.
View Article and Find Full Text PDFNoradrenergic suppression to reduce electroencephalographic arousal after intubation: a randomised, placebo-controlled trial.
BJA Open
March 2025
Department of Anaesthetics, Royal Prince Alfred Hospital, Sydney, NSW, Australia.
Background: Intraoperative awareness, without explicit recall, occurs after induction of anaesthesia in approximately 10% of persons under 40 yr of age. Most anaesthetic agents minimally suppress the noradrenergic system. We hypothesised that addition of dexmedetomidine, which suppresses noradrenergic activity, may reduce encephalographic (EEG) arousal in response to tracheal intubation; such an effect would lay the foundation for future studies of dexmedetomidine in reducing intraoperative awareness.
View Article and Find Full Text PDFMind in others' shoes: Neuroscientific protocol for external referent decision awareness (ERDA) in organizations.
Neuroscience
January 2025
International research center for Cognitive Applied Neuroscience (IrcCAN), Università Cattolica del Sacro Cuore, Milan, Italy; Research Unit in Affective and Social Neuroscience, Department of Psychology, Università Cattolica del Sacro Cuore, Milan, Italy.
This study investigates the neural and physiological mechanisms underlying External Referent Decision Awareness (ERDA) within organizational contexts, focusing on hierarchical roles (Head, Peer, Staff). Twenty-two professionals participated, and electroencephalographic (EEG frequency band: Delta, Theta, Alpha, Beta, Gamma) and autonomic indices (skin conductance and cardiovascular indices) were recorded, while personality traits and decision-making styles were assessed. Results revealed higher Delta and Theta activation in the left temporo-parietal junction (TPJ) during Peer-related decisions, reflecting increased social cognition and ambiguity regulation in those contexts.
View Article and Find Full Text PDFComparison of midazolam and dexmedetomidine combined with thoracic paravertebral block in hemodynamics, inflammation and stress response, and cognitive function in elderly lung cancer patients.
Int Immunopharmacol
January 2025
Department of Supervision Office, Changsha Health Vocational College, Changsha City, 410600, Hunan Province, China. Electronic address:
Objective: This study aimed to compare the clinical outcomes of midazolam and dexmedetomidine combined with ropivacaine-induced thoracic paravertebral nerve block (TPVB) in radical lung cancer surgery.
Methods: To retrospectively analyze the clinical data of elderly patients who underwent thoracoscopic radical lung cancer surgery from March 2020 to February 2023 in our hospital. All patients underwent a single two-site method of TPVB at the levels of T4 and T7 under ultrasound guidance.
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