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On the causal connection in lifespan correlations and the possible existence of a 'number of life' at molecular level.

Sci Rep

December 2024

Departamento de Astronomía, Universidad de Chile, Casilla 36-D, Santiago, Chile.

Multiple physiological traits correlates with lifespan, being unclear both the causal connection among them and with the process of ageing. In this paper, we show that six traits (such as metabolic rate, mass, heart rate, etc) acting at the system level, are all related to lifespan thru the existence of an approximately constant number of respiration cycles in a lifespan ([Formula: see text]), therefore, we find that those relationships are not independently related to ageing. In addition, we study if the approximately constant [Formula: see text] is possibly linked with the end-of-lifespan somatic mutation burden, another number recently found to be approximately constant (Cagan, Nature 604:517-524, 2022).

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The aim of this experiment was to investigate the effects of rumen fluid and molasses on the nutrient composition, fermentation quality, and microflora of Caragana korshinskii Kom. The trial included four treatments: a control group (CK) without additives and experimental groups supplemented with 7% rumen fluid (R), 4% molasses (M), and 7% rumen fluid + 4% molasses (RM). 15 days and 60 days of ensiling.

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EMG feedback improves force control of a myoelectric hand prosthesis by conveying the magnitude of the myoelectric signal back to the users via tactile stimulation. The present study aimed to test if this method can be used by a participant with a high-level amputation, and whose muscle used for prosthesis control (pectoralis major) was not intuitively related to hand function. Vibrotactile feedback was delivered to the participant's torso, while the control was tested using EMG from three different muscles.

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This study investigates the ablation performance of Inconel 718, a nickel-based superalloy, and metal matrix polycrystalline diamond (MMPCD), a super composite, using a nano-second (ns) pulsed laser across a range of ablation conditions. Single trenches varying in energy fluence and scanning speeds were created, analyzing the experimental responses in terms of ablation rate and surface roughness. Using regression techniques, models were developed to understand these relationships.

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The Crimean Congo virus has been reported to be a part of the spherical RNA-enveloped viruses from the Bunyaviridae family. Crimean Congo fever (CCHF) is a fatal disease with having fatality rate of up to 40%. It is declared endemic by the World Health Organization.

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