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Applying Multi-Purpose Commercial Inertial Sensors for Monitoring Equine Locomotion in Equestrian Training.
Sensors (Basel)
December 2024
Department of Engineering and Industrial Design, Magdeburg-Stendal University of Applied Sciences, 39110 Magdeburg, Germany.
Inappropriate, excessive, or overly strenuous training of sport horses can result in long-term injury, including the premature cessation of a horse's sporting career. As a countermeasure, this study demonstrates the easy implementation of a biomechanical load monitoring system consisting of five commercial, multi-purpose inertial sensor units non-invasively attached to the horse's distal limbs and trunk. From the data obtained, specific parameters for evaluating gait and limb loads are derived, providing the basis for objective exercise load management and successful injury prevention.
View Article and Find Full Text PDFAre Junior Tennis Players Less Exposed to Shocks and Vibrations than Adults? A Pilot Study.
Sensors (Basel)
December 2024
Université de Lyon, UCBL1 Laboratoire Inter Universitaire de Biologie de la Motricité, EA 7424, 69100 Villeurbanne Cedex, France.
This study investigated muscle activation, shocks, and vibrations of the upper extremities during tennis serves between junior and adult tennis players. Thirty-five well-trained tennis players (15 juniors and 20 adults) performed 10 maximal successful tennis serves. Two triaxial accelerometers recorded the shock and vibration on the racket and the hand on the dominant side.
View Article and Find Full Text PDFUnveiling the Potential of C Factor Applied to Pilot Bioavailability/Bioequivalence Studies-A Case Study with Pazopanib Drug Products.
Pharmaceutics
December 2024
Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, 1649-003 Lisbon, Portugal.
When companies are uncertain about the potential of a new formulation to be bioequivalent to a Reference product, it is common practice to carry out downsized pilot studies as a gatekeeping in vivo strategy to decide whether to move forward or not with a full-size pivotal study. However, due to the small study size, these studies are inarguably more sensitive to variability. To address and mitigate the uncertainty of the conclusions of pilot studies concerning the maximum observed concentration (C), the factor was proposed as an alternative approach to the average bioequivalence statistical methodology.
View Article and Find Full Text PDFAlkali-Polymer Flooding in an Austrian Brownfield: From Laboratory to Field-Insights.
Polymers (Basel)
December 2024
OMV Exploration & Production GmbH, 1020 Vienna, Austria.
We focus on optimizing oil displacement in brownfields using alkali polymers (AP) flooding. The goal is to enhance rock-fluid and fluid-fluid interactions to improve oil recovery. The evaluation includes detailed screening of AP mixtures to ensure cost-effectiveness and maximize chemical slug efficiency, using an AP pilot project in Austria as a case study.
View Article and Find Full Text PDFSwitchable Solvent for Separation and Extraction of Lignin from Lignocellulose Biomass: An Investigation of Chemical Structure and Molecular Weight.
Polymers (Basel)
December 2024
State Key Laboratory of Biobased Material and Green Papermaking, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250353, China.
Lignin, the most abundant natural aromatic polymer, holds considerable promise for applications in various industries. The primary obstacle to the valorization of lignin into useful materials is its low molecular weight and diminished chemical reactivity, attributable to its intricate structure. This study aimed to treat lignocellulosic biomass using a switchable solvent (DBU-HexOH/HO) derived from the non-nucleophilic superbase 1,8-diazabicyclo [5.
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