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Pityriasis versicolor (PV) is a common skin condition associated with Malassezia species. Factors influencing PV development, such as sebum and skin hydration levels, are not fully understood, especially among adolescents. This study aimed to determine Malassezia speciation and assess sebum and hydration levels in secondary school students with PV in Ibadan, Nigeria.

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Article Synopsis
  • Tinea capitis is a fungal infection common in children, and this study aimed to determine its prevalence among schoolchildren in Lomé, Togo, along with identifying the fungi involved and the related risk factors.
  • A cross-sectional study was conducted with 15,087 pupils, revealing a prevalence of 3.08% for tinea capitis, primarily caused by Trichophyton mentagrophytes.
  • The research identified risk factors such as living with pets, infrequent bathing, previous ringworm infections, sharing hygiene items, and having similar lesions in the same household, indicating a need for targeted preventive measures.
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Article Synopsis
  • The original publication discusses key themes and findings that are essential to understanding the subject matter.
  • It outlines the methodology used in the research, highlighting the importance of data collection and analysis.
  • The text also emphasizes the implications of the findings for future studies and their relevance in the broader context of the field.
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In Situ Expression of TNF-α and IL-10 in Human Dermatophytosis Lesions due to Trichophyton rubrum.

Mycopathologia

October 2024

Laboratório de Investigação Médica LIM 53, Divisão de Clínica Dermatológica, Instituto de Medicina Tropical, Faculdade de Medicina, Hospital das Clínicas, Universidade de São Paulo, São Paulo, São Paulo, Brasil.

Dermatophytosis is a very common superficial mycosis, but there are few studies about the human immune response to dermatophytes. We aim to analyze the in situ expression of TNF-α and IL-10 in human dermatophytosis. Expression of TNF-α and IL-10 were evaluated in skin samples from 10 patients with dermatophytosis and 12 healthy subjects using an immunohistochemistry assay.

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The emergence of high-resistance strains to known antifungal drugs has highlighted the urgency of developing novel therapies for chronic dermatophytosis as a global health problem. An experimental dermatophytosis model in guinea pigs was developed to investigate the in vivo wound healing effects of cold atmospheric plasma (CAP) on T. rubrum skin invasion.

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