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BMJ Open Diabetes Res Care
December 2024
Department of Internal Medicine, Radboud University Medical Center, Nijmegen, Gelderland, Netherlands.
Introduction: Maturity-onset diabetes of the young (MODY) and neonatal diabetes mellitus (NDM) are the most prevalent causes of monogenic diabetes. MODY is an autosomal dominant condition with onset in childhood and young adulthood, while NDM is defined with diabetes onset within 6 months of age and can be caused by dominant, recessive, X-linked genes or by chromosomal abnormalities. Here, we describe a rare case of monogenic diabetes in a patient who is homozygous for an gene variant.
View Article and Find Full Text PDFRev Panam Salud Publica
December 2024
Organización Panamericana de la Salud Washington D.C. Estados Unidos de América Organización Panamericana de la Salud, Washington D.C., Estados Unidos de América.
Objective: To describe the process of restructuring the National Expert Committee and its impact on the causality assessment of events supposedly attributable to vaccination or immunization (ESAVI) in the context of vaccine safety monitoring during the COVID-19 pandemic, 2020-2023.
Method: A report was prepared on the experience of creating and operating Mexico's National Expert Committee during the aforementioned period.
Results: During the 2020-2023 period, 1293 severe ESAVIs were reported after COVID-19 vaccination; after 98.
Harefuah
December 2024
Maccabi Healthcare Services Sharon Region, Hebrew University Faculty of Medicine, and Medint Medical Intelligence, Tel Aviv, Israel.
Adrenoleukodystrophy is a genetic metabolic disorder characterized by a heterogeneous phenotype. Its severe form, known as cerebral adrenoleukodystrophy, involves unpredictable cerebral damage and progressive central nervous system deterioration. This rare condition became famous because of a Hollywood movie in which the Italian parents of a child with the condition supposedly discovered a medication for treating the condition.
View Article and Find Full Text PDFRev Panam Salud Publica
December 2024
Departamento de gestión de la información y epidemiología Hospital General San Felipe Tegucigalpa Honduras Departamento de gestión de la información y epidemiología, Hospital General San Felipe, Tegucigalpa, Honduras.
Objective: To describe the continuing education strategies implemented as part of the academic training of health workers; related barriers and facilitators; and the perceptions of health workers in sentinel hospitals in Honduras regarding changes in their knowledge.
Methods: The implemented continuing education strategies are described, as are the findings of a questionnaire given to assess health workers' perceptions of the effectiveness of these strategies in the acquisition of knowledge, skills, and competencies related to the surveillance of events supposedly attributable to vaccination, immunization, or adverse events of special interest. Barriers to participation in these strategies is also described.
Rev Panam Salud Publica
December 2024
Programa especial de inmunización integral Organización Panamericana de la Salud Washington D.C. Estados Unidos de América Programa especial de inmunización integral, Organización Panamericana de la Salud, Washington D.C., Estados Unidos de América.
In Honduras, health systems have been faced with a duty and a need to establish surveillance mechanisms in order to understand the pathways of health and disease in the population. The objective of this article is to describe the process of analysis and the strategies used during development of a robust information system for vaccine safety surveillance, which can also be replicated for other forms of surveillance. For this purpose, agile development methods and open-source tools were used to design and develop a baseline monitoring system, incorporating recognized standards for information coding, validation, and verification.
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