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-Loaded Easily Injectable Hydrogel Promotes Endometrial Repair via Long-Term Retention and Microenvironment Modulation.
ACS Nano
January 2025
Guangdong Provincial Key Laboratory of Reproductive Medicine, Guangdong Provincial Clinical Research Center for Obstetrical and Gynecological Diseases, Department of Gynecology & Obstetrics, Reproductive Medicine Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, PR China.
Regeneration of the injured endometrium, particularly the functional layer, is crucial for the prevention of uterine infertility. At present, clinical treatment using sodium hyaluronate hydrogel injection is limited by its relatively low fluidity, short-term retention, and insufficient bioactive ingredients, so it is necessary to develop an advanced healing-promoting hydrogel. The modulation of the microenvironment by presents a bioactive component that can facilitate the regeneration of the functional layer.
View Article and Find Full Text PDFAberrant acetylation caused by a CDYL splicing mutation contributes to thin mid-piece related asthenoteratozoospermia and male infertility.
Andrology
January 2025
Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Objectives: Acetylated tubulin is a hallmark of flagellar stability in spermatozoa, and studies have demonstrated the ability of CDYL to function as a tubulin acetyltransferase in spermatozoa. Of note, germline conditional knockout of Cdyl can lead to asthenoteratozoospermia and infertility in male mice. However, the role of CDYL gene in human fertility remains uncharacterized.
View Article and Find Full Text PDFPersistent, sterile necrotizing granulomatous dermatitis following treatment of 20-year infection.
JAAD Case Rep
November 2024
Department of Dermatology, University of Utah School of Medicine, Salt Lake City, Utah.
Evaluating platelet concentrates by platelet indices, thromboelastography, and flow cytometry.
Asian J Transfus Sci
May 2023
Department of Hematology, All India Institute of Medical Sciences, New Delhi, India.
Introduction: Platelet transfusion has been therapeutically used in patients with thrombocytopenia and platelet function defects over the years. The use of advanced techniques may add value in assessing the quality of platelet products. The aim of the study was to assess stored platelet concentrates (PCs) prepared in blood banks for platelet indices, clot strength, and platelet function.
View Article and Find Full Text PDFOptimized nursing management in the Central Sterile Supply Department and Gastroenterology Department: a retrospective controlled study.
Am J Transl Res
December 2024
Endoscopy Center of Gastroenterology Department, General Hospital of Central Theater Command Wuhan 430070, Hubei, China.
Objective: To evaluate the impact of optimized nursing management involving the Central Sterile Supply Department (CSSD) and Gastroenterology Department on sterilization processes, nurse well-being, and patient satisfaction.
Methods: This retrospective study analyzed data from 40 CSSD nurses and sterilization metrics for 1,017 gastroenterology instruments before and after implementing optimized management. The study included a control group (CG) prior to the intervention and an experimental group (EG) after.
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