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Frequent Hand Hygiene-Induced Skin Symptoms and Alterations in Hand Microbiota: A Neglected Form of Chronic Occupational Exposure Among Health Care Workers.

J Nurs Care Qual

March 2025

Author Affiliations: Department of Colorectal and Anal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China (Dr He); Department of Infection Prevention and Control Management, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China (Mr Lin, Mss Chen, Li, Cheng, Tan, and Dr Wang); School of Public Health, Hubei University of Medicine, Shiyan, Hubei, China (Mr Lin, Ms Chen, Dr Wu); Department of Nursing, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China (Dr Feng, Ms Chen); Hubei Engineering Center for Infectious Disease Prevention, Control and Treatment, Wuhan, Hubei, China (Drs Feng, Wang); Health Science Center, Yangtze University, Jingzhou, Hubei, China (Ms Zhang); and Sinopharm Dongfeng General Hospital (Hubei Clinical Research Center of Hypertension), Hubei University of Medicine, Shiyan, Hubei, China (Dr Wu).

Background: Frequent hand hygiene is essential for infection control among health care workers (HCWs) but may cause adverse skin effects.

Purpose: To assess the relationships between frequent hand hygiene practices, skin symptoms, and microbiota alterations in HCWs.

Methods: A comprehensive search of 7 databases was conducted to identify articles published between January 2014 and July 2024 in English and Chinese.

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Panton-Valentine Leukocidin in Necrotizing Pneumonia: A Case Report.

Cureus

February 2025

Department of Intensive Care Medicine, Unidade Local de Saúde Loures Odivelas, Loures, PRT.

Panton-Valentine leukocidin (PVL)-producing is a rare but clinically significant cause of community-acquired pneumonia (CAP). This toxin leads to extensive tissue destruction and severe inflammation, often progressing to necrotizing pneumonia, septic shock, and multiorgan failure, representing a challenge in medical practice due to its rapid progression and poor prognosis. We discuss a case of a 65-year-old diabetic male who developed severe CAP leading to septic shock, respiratory failure, and multiorgan dysfunction.

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Bioactive antimicrobial films play important roles in various fields, such as biodegradable interfaces, tissue regeneration, and biomedical applications where preventing infection, biocompatibility, and immune rejection are important. In the present study, bioactive POSS-doped TiCT MXene filled PLA composite film was prepared using the solution casting method for biomedical applications. The contact angle tests were investigated to reveal the usability of the thin films in biomedical applications.

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Microbiological characteristics of pleural infection in adults: A 10-year retrospective study from a tertiary respiratory care hospital.

Respir Med Res

February 2025

Microbiology Laboratory, Abderrahmen Mami Pneumology and Phthisiology Hospital, 2080, Ariana, Tunisia; Faculty of Pharmacy, University of Monastir, 5000, Monastir, Tunisia.

Introduction: Pleural infection is a high-mortality disease with a rising incidence in the past two decades. The knowledge of the main causative organisms is an important step for appropriate treatment. This study aims to describe etiologic and antibiotic resistance features of non-tuberculous pleural infections in adults in a tertiary care center specializing in the treatment of respiratory diseases.

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Background: Dacryolithiasis can occur anywhere in the lacrimal drainage system and is frequently associated with microbial infections. The presence of dacryolithiasis is difficult to determine based on its clinical manifestations, which complicates clinical treatment.

Objectives: To analyze the clinical diagnosis, treatment and characteristics of dacryolithiasis, as well as surgical methods used to treat it and treatment effects over the past 5 years.

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