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[Dynamics of ultrastructural organization of liver cells in experimental peritonitis].
Eksp Klin Gastroenterol
July 2014
In the experiment on Wistar rats by methods of light and electron microscopy an ultrastructural disorders of the liver cells in various stages of peritonitis were investigated. It was shown that the reactive phase of experimental peritonitis associates with dystrophic changes of the hepatocytes and the endotheliocytes of sinusoids. These reversible changes are explained by an adaptive response of cells to inflammation.
View Article and Find Full Text PDFDielectrophoresis of DNA: Quantification by impedance measurements.
Biomicrofluidics
June 2010
Fraunhofer Institute for Biomedical Engineering, D-14476 Potsdam, Germany.
Dielectrophoretic properties of DNA have been determined by measuring capacitance changes between planar microelectrodes. DNA sizes ranged from 100 bp to 48 kbp, DNA concentrations from below 0.1 to 70 mugml.
View Article and Find Full Text PDFUltrastructural changes in dysferlinopathy support defective membrane repair mechanism.
J Clin Pathol
February 2005
Clinical Department of Radiological and Histocytopathological Sciences, University of Bologna, 40138 Bologna, Italy.
Background: The dysferlin gene has recently been shown to be involved in limb girdle muscular dystrophy type 2B and its allelic disease, Miyoshi myopathy, both of which are characterised by an active muscle degeneration and regeneration process. Dysferlin is known to play an essential role in skeletal muscle fibre repair, but the process underlying the pathogenetic mechanism of dysferlinopathy is not completely understood.
Aims: To define both specific alterations of muscle fibres and a possible sequential mechanism of myopathy development.
Gluten sensitivity and 'normal' histology: is the intestinal mucosa really normal?
Dig Liver Dis
November 2003
Section of Anatomy and Histology, Department of Morphological and Biomedical Sciences, University of Verona, Verona, Italy.
Background: Early pathogenetic events of gluten intolerance may be overlooked in patients with serologic markers of celiac disease and normal intestinal mucosa by both conventional histology and immunohistochemistry.
Aims: To investigate if a submicroscopical damage of the absorptive cell surface was associated with developing gluten sensitivity.
Patients And Methods: Duodenal biopsies of seven subjects with positive anti-endomysial antibodies and normal histology underwent ultrastructural evaluation of the epithelial surface by means of both scanning and transmission electron microscopy.
[Confirmation of a prenatal diagnosis of trisomy 13 with comparative genomic hybridization (CGH)].
Orv Hetil
May 2001
Altalános Orvostudományi Kar, I. Szülészeti- és Nógyógyászati Klinika, Semmelweis Egyetem, Budapest.
Trisomy 13 was diagnosed with genetic amniocentesis in a fetus of a 50 years old patient. Fetopathologic examination has shown cyclopy, proboscis and semilobar holoprosencephaly of the fetus, which is consistent with Patau syndrome. DNA was extracted from frozen liver tissue.
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