Air pollution is associated with cardiovascular mortality. Inhaled ultrafine particles translocate into the blood. Amine-polystyrene ultrafine particles significantly enhance experimental thrombus formation in a damaged hamster vessel and shorten the closure time in the Platelet Function Analyser. Diesel exhaust particles are thrombogenic within one hour of intratracheal instillation and shorten the closure time ex vivo. These experimental observations provide a plausible biological explanation for the epidemiologically established link between air pollution and acute myocardial infarction.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1159/000073597 | DOI Listing |
Publication Analysis
Top Keywords
air pollution
12
ultrafine particles
8
shorten closure
8
closure time
8
pollution thrombosis
4
thrombosis experimental
4
experimental approach
4
approach air
4
pollution associated
4
associated cardiovascular
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!