AI Article Synopsis
- Researchers developed a vaccination method for bacterial coldwater disease (BCWD) in ayu fish (Plecoglossus altivelis) by using formalin-killed cells (FKCs) of Flavobacterium psychrophilum.
- The FKC was administered orally at a dose of 0.1-0.2 g/kg body weight to juvenile ayu for either two weeks continuously or five days within that period.
- The vaccinated fish showed significantly higher survival rates after being subjected to immersion challenges compared to control groups, demonstrating the effectiveness of oral vaccination against BCWD.
Article Abstract
The development of a practical vaccination method against bacterial coldwater disease (BCWD) in ayu Plecoglossus altivelis and the efficacy of oral administration of formalin-killed cells (FKCs) of Flavobacterium psychrophilum was investigated. The FKC was administrated at a dose of 0.1-0.2 g kg(-1) body weight to juvenile ayu (0.5 g body weight) every day for 2 wk or on 5 days over 2 wk. Experimental immersion challenge at 3 and 7 wk after vaccination showed significantly higher survival rates than the controls. The results show the effectiveness of oral vaccination against BCWD in ayu.
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| http://dx.doi.org/10.3354/dao055261 | DOI Listing |
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