In June 2002, the Arkansas Department of Health anticipated a West Nile virus epidemic based on diagnoses in birds and increasing reports of human disease cases in neighboring states. Department officials activated an emergency operations center (EOC) dedicated to human West Nile virus surveillance. As a result, 43 cases (33 West Nile meningoencephalitis and 10 West Nile fever) and five (12%) deaths were confirmed from 16 counties. For all cases, the median age was 54 years (range: 2-93 years). County-specific incidence of West Nile meningoencephalitis ranged from 0.6-15.9 cases per 100,000 people. The implemented system for enhanced West Nile virus surveillance will serve as a model for future epidemic years.

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