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Analysis of Urinary Metanephrines Using Liquid Chromatography Tandem Mass Spectrometry.
Methods Mol Biol
January 2025
Analytic Biochemistry, Calculi and Manual Chemistry, Mass Spectrometry, ARUP Laboratories, Inc., Salt Lake City, UT, USA.
Metanephrines (metanephrine [MN] and normetanephrine [NMN]) are O-methylated metabolites derived from the catecholamines, epinephrine, and norepinephrine, respectively. High concentrations of metanephrines have been observed in individuals with pheochromocytoma, a neuroendocrine tumor. Measurement of metanephrines in urine is used to screen for the tumor.
View Article and Find Full Text PDFImpact of comprehensive thermal insulation on stress response and immune function in hysteroscopy patients: A retrospective study.
Medicine (Baltimore)
November 2024
Department of Obstetrics and Gynecology, Xinyu Maternal and Child Health Hospital, Xinyu, Jiangxi, China.
This retrospective study explores the impact of comprehensive thermal insulation measures on the stress response of patients undergoing hysteroscopy surgery. A total of 600 patients who underwent hysteroscopy at our hospital from January 2018 to December 2022 were included. Participants were randomly assigned to an observation group (n = 305) and a control group (n = 295).
View Article and Find Full Text PDFEarly rebleeding rate following endoscopic treatment of colonic diverticular bleeding: a systematic review and meta-analysis.
Ann Gastroenterol
December 2024
Department of Hepatology and Gastroenterology, CHU Saint-Pierre, Brussels, Belgium (Jennifer Aoun, Pierre Eisendrath).
Background: Various endoscopic treatment options are available for managing colonic diverticular bleeding (CDB). We conducted a systematic review and meta-analysis to assess the effectiveness of these endoscopic interventions in achieving hemostasis in patients with CDB, focusing on early rebleeding rate (ERR) within 30 days.
Methods: A systematic literature search of the PubMed and Cochrane Library databases was performed for articles published between January 2008 and December 2023.
Hazelnut oral immunotherapy desensitizes hazelnut but not other tree nut allergies (Nut CRACKER Study).
J Allergy Clin Immunol Pract
January 2025
Institute of Allergy, Immunology and Pediatric Pulmonology, Yitzhak Shamir Medical Center; Department of Pediatrics, Faculty of Medicine, Tel Aviv University.
Background: Data on oral immunotherapy (OIT) for hazelnut allergy is limited and its potential to cross-desensitize for other nuts is unknown.
Objective: To study the efficacy and safety of hazelnut OIT in desensitizing hazelnut and additional tree nuts.
Methods: A prospective observational study of 30 hazelnut allergic patients aged ≥4 years who underwent hazelnut OIT.
Establishing In-vivo brain microdialysis for comparing concentrations of a variety of cortical neurotransmitters in the awake rhesus macaque between different cognitive states.
J Neurosci Methods
January 2025
Cognitive Neuroscience Laboratory, German Primate Center - Leibniz Institute for Primate Research, Goettingen, Germany; Faculty of Biology and Psychology, University of Goettingen, 37077 Goettingen, Germany.
Background: Neuronal activity is modulated by behavior and cognitive processes. The combination of several neurotransmitter systems, acting directly or indirectly on specific populations of neurons, underlie such modulations. Most studies with non-human primates (NHPs) fail to capture this complexity, partly due to the lack of adequate methods for reliably and simultaneously measuring a broad spectrum of neurotransmitters while the animal engages in behavioral tasks.
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