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Increased plasma interleukin-1β is associated with accelerated lung function decline in non-smokers.

Pulmonology

December 2025

State Key Laboratory of Respiratory Disease & National Clinical Research Center for Respiratory Disease & National Center for Respiratory Medicine & Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

Interleukin-1β is one of the major cytokines involved in the initiation and persistence of airway inflammation in chronic obstructive pulmonary disease (COPD). However, the association between plasma interleukin-1β and lung function decline remains unclear. We aimed to explore the association between plasma interleukin-1β and lung function decline.

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Brazilian soils have distinctive characteristics to European and North American soils which are typically used to investigate pesticide fate. This study aimed to compare soil-water partition coefficient (K), reversibility of adsorption and degradation half-life (DT) of 5 pesticides covering a wide range of physico-chemical properties in contrasting Brazilian soils (Argissolo, Gleissolo, Latossolo and Neossolo) and a temperate (UK) alfisol soil, and to study their relationship with soil OM, clay and expandable clay content, CEC and pH. In addition, we used a novel laboratory test to evaluate sorption reversibility, the 3-Phase Assay (3PA).

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Climate change and waterborne diseases in temperate regions: a systematic review.

J Water Health

January 2025

Global Institute for Water Security, University of Saskatchewan, 11 Innovation Boulevard, Saskatoon, Saskatchewan S7N 3H5, Canada; Schulich School of Engineering, University of Calgary, 622 Collegiate Pl NW, Calgary, Alberta T2N 4V8, Canada.

Risk of waterborne diseases (WBDs) persists in temperate regions. The extent of influence of climate-related factors on the risk of specific WBDs in a changing climate and the projections of future climate scenarios on WBDs in temperate regions are unclear. A systematic review was conducted to identify specific waterborne pathogens and diseases prevalent in temperate region literature and transmission cycle associations with a changing climate.

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Blood clots (BCs) play a crucial biomechanical role in promoting osteogenesis and regulating mesenchymal stem cell (MSC) function and fate. This study shows that BC formation enhances MSC osteogenesis by activating Itgb1/Fak-mediated focal adhesion and subsequent Runx2-mediated bone regeneration. Notably, BC viscoelasticity regulates this effect by modulating Runx2 nuclear translocation.

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Mesophilic anaerobic digestion of mixed sludge in CSTR and AnMBR systems: A perspective on microplastics fate.

J Environ Manage

January 2025

CALAGUA - Unitat Mixta UV-UPV, Departament d'Enginyeria Química, Universitat de València, Avinguda de la Universitat s/n, Burjassot, Valencia, 46100, Spain.

Most microplastics (MPs) end up in the biosolids produced in wastewater treatment plants (WWTPs) and can pose contamination risks when the biosolids are applied to agriculture. This study evaluated the impact of mesophilic anaerobic digestion on the fate of MPs in WWTP sludge. For this, two laboratory-scale anaerobic digesters were operated in parallel, consisting of a continuous stirred tank reactor (CSTR) and a membrane bioreactor (AnMBR) equipped with an ultrafiltration membrane to decouple the hydraulic and sludge retention times.

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