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Sex and the Risk of Atheromatous and Nonatheromatous Cardiovascular Disease in CKD: Findings From the CKD-REIN Cohort Study.

Am J Kidney Dis

November 2024

Centre for Research in Epidemiology and Population Health, Paris-Saclay University, Institut National de la Santé et de la Recherche Médicale (INSERM) U1018, Clinical Epidemiology Team, Versailles Saint-Quentin University, Villejuif.

Article Synopsis
  • The study investigates how chronic kidney disease (CKD) affects sex differences in cardiovascular disease (CVD) risk, specifically distinguishing between atheromatous CVD (ACVD) and nonatheromatous CVD (NACVD).
  • Utilizing data from a cohort of nearly 3,000 patients with moderate to severe CKD across France, the results indicate that women have a significantly lower rate of ACVD compared to men, but no significant difference in NACVD rates was found between the sexes.
  • The findings highlight that as kidney function declines (measured by eGFR), the sex differences in ACVD risk diminish, whereas NACVD risk remains consistent across both sexes, suggesting gender impacts risk differently based on CVD
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Nonatheromatous Popliteal Artery Disease.

Ann Vasc Surg

February 2022

Department of Vascular and Endovascular Surgery, First Affiliated Hospital of Zhengzhou University, Henan, China.

Objective: Peripheral artery disease (PAD) is often caused by atherosclerosis. However, causes other than atherosclerosis is often overlooked. Popliteal artery entrapment syndrome (PAES) and popliteal artery adventitial cystic disease (PACD) are two common nonatheromatous causes of claudication and critical limb ischemia.

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Cystic Arterial Disease Located Only in the Media of the Popliteal Artery: A Case Report.

Ann Vasc Dis

December 2019

Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Fukuoka, Japan.

Adventitial cystic disease of the popliteal artery is a rare non-atheromatous peripheral artery disease. In most cases, the cystic lesion is located in the adventitia of the popliteal artery. Herein, we present a rare case of cystic arterial disease in which the cyst was located only in the media of the popliteal artery.

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The Common Femoral Artery Bifurcation Lesions: Clinical Outcome of Simple Versus Complex Stenting Techniques - An Analysis Based on the TECCO Trial.

Ann Vasc Surg

April 2020

Hôpital Paris Saint Joseph, service de chirurgie vasculaire et endovasculaire, Paris, France; Laboratoire de Physiopathologie de la Résorption Osseuse, Inserm-UN UMR-957, Nantes, France. Electronic address:

Background: Common femoral artery (CFA) stenting appears as a promising alternative treatment to the open surgery for de novo CFA stenosis. The stenting of lesions just located at the CFA is simple, whereas stenting of CFA bifurcation lesions is more complex, and outcomes are still matter of debate. The aim of this study was to describe and to compare clinical outcomes of techniques used to treat simple over complex lesions for the stenting of CFA lesions.

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Prevalence of atheromatous and non-atheromatous cardiovascular disease by age in chronic kidney disease.

Nephrol Dial Transplant

May 2020

Service de Néphrologie-Dialyse, CHU Ambroise Paré, APHP, Boulogne-Billancourt, France.

Background: Although chronic kidney disease (CKD) and age are major risk factors for cardiovascular disease (CVD), little is known about the relative proportions of atheromatous and non-atheromatous CVD by age in CKD patients.

Methods: We used baseline data from the French Chronic Kidney Disease-Renal Epidemiology and Information Network (CKD-REIN) cohort of 3033 patients (65% men) with CKD Stages 3-4 to study crude and adjusted associations between age, the estimated glomerular filtration rate (eGFR), atheromatous CVD (coronary artery disease, peripheral artery disease and stroke) and non-atheromatous CVD (heart failure, cardiac arrhythmia and valvular heart disease).

Results: Mean age was 66.

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