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Article Synopsis
- Ascariasis, a parasitic infection caused by a helminth, is commonly found in tropical and subtropical regions, often linked to poverty and poor sanitation.* ! -
- While it generally resides harmlessly in the small intestine, it can cause severe complications like intestinal blockage and can even migrate to other organs, leading to conditions such as cholangitis and pancreatitis.* ! -
- A case study describes a 4.5-year-old boy from India who experienced acute abdominal pain, vomiting, and constipation due to ascariasis, showing the infection's impact on children's health.* !
Th2-biased immune responses to body migrating Ascaris larvae in primary infection are associated with pathology but not protection.
Sci Rep
June 2024
Institute of Immunology, Centre for Infection Medicine, Department of Veterinary Medicine, Freie Universität Berlin, Berlin, Germany.
Article Synopsis
- Helminth infections cause parasites to be unevenly distributed in hosts, prompting a study to see if early immune responses to Ascaris larvae lead to this pattern in susceptible vs. resistant mouse strains.
- Susceptible C57BL/6 mice showed a stronger immune response to the larvae compared to resistant CBA mice, which was linked to greater pathology, including higher levels of eosinophils in various tissues.
- Despite the increased immune response in susceptible mice, eosinophils were found to not be essential for controlling Ascaris larvae, indicating that a strong type 2 immune response can lead to more harm than good during early infection stages.
Abdominal complications of ascariasis in childhood.
J Pediatr (Rio J)
August 2024
Universidade Federal do Rio de Janeiro (UFRJ), Faculdade de Medicina, Departamento de Cirurgia, Rio de Janeiro, RJ, Brazil.
Objective: Complications of ascariasis are a significant cause of abdominal pain in pediatric emergencies, especially where it is endemic. A literature review was conducted with the aim of improving diagnostic and therapeutic approaches for these patients.
Data Sources: A PubMed search was conducted using the key terms "ascariasis complications" and "hepatobiliary ascariasis".
Ascariasis causing small bowel obstruction in an adult female: A case report.
Int J Surg Case Rep
August 2023
Department of Medicine, School of Medicine, College of Medicine and Health Sciences, Mizan-Tepi University, Mizan Teferi, Ethiopia.
Introduction And Importance: Ascariasis is a helminthic infection of humans caused by Ascaris lumbricoides. Intestinal obstruction from ascariasis can result in a rare but severe and often fatal surgical emergency of intestinal perforation and peritonitis in endemic areas. There have been reports of ascariasis causing Small Bowel Obstruction (SBO) in children in endemic areas but this phenomenon has not been studied in adults.
View Article and Find Full Text PDFAscaris lumbricoides a rare cause ileal perforation, a case report.
Int J Surg Case Rep
April 2023
Department of Pathology, University of Gondar, Collage of Medicine and Health Sciences, Gondar, Ethiopia.
Introduction And Importance: Ascariasis is a helminthic infection of humans caused by Ascaris lumbricoides. Pediatric patients infected with Ascaris can develop multiple complications including appendicitis, gastrointestinal bleeding, hepatobiliary disease like cholangitis or obstructive jaundice, intussusception, and bowel obstruction among others. Ascaris is a rare cause of intestinal perforation even in endemic areas.
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