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Health economics assessment study of teicoplanin versus vancomycin in Gram-positive infections.
Rev Esp Quimioter
March 2006
Servicios Farmacología Clínica, Hospital Clínico San Carlos, Madrid, Spain.
The objective of this study, conducted at Hospital Clínico San Carlos, Madrid, Spain, was to compare the cost of treatment of Gram-positive infections with teicoplanin and vancomycin under normal conditions. Using a prospective observational study design for drug utilization and economic assessment, we evaluated the comparability of the sample, adverse events, features of treatment with teicoplanin/vancomycin and factors influencing the consumption of resources until the end of glycopeptide treatment or discharge (whichever occurred later) using Health System perspective. Costs were assigned using the hospital's evaluation at the time of the study.
View Article and Find Full Text PDF[Improving the interlaboratory variation for creatinine serum assay].
Ann Biol Clin (Paris)
August 2004
Département de biologie clinique, Institut Claudius Regaud, (CRLCC Midi-Pyrénées), Toulouse.
Purpose: To assess inter-assay variation and accuracy of blood creatinine measurements as well as the effect of the standardization of the calibration procedures on inter-assay variation.
Methods: Inter-assay variation and accuracy were assessed using 30 frozen human sera and 3 certified reference materials, which were analysed by 17 creatinine assays (colorimetric: 12, enzymatic: 4, HPLC: 1). Usual calibration procedure was compared with two common calibration procedures using either a reference material (404.
Normal renal function 8 to 13 years after cyclosporin A therapy in 285 diabetic patients.
Diabetes Metab Res Rev
July 2003
Service de Diabétologie, Hôpital Bichat, Paris, France.
Background: Cyclosporin A (CyA) may induce acute nephrotoxicity. The question has been raised of the possible long-term unfavorable course of CyA-induced lesions. Advantage was taken of a large cohort of diabetic patients treated for several months using moderate CyA dosage to evaluate the long-term evolution of renal function in such patients.
View Article and Find Full Text PDFA prospective randomized trial on azathioprine addition to cyclosporine versus cyclosporine monotherapy at steroid withdrawal, 6 months after renal transplantation.
Transplantation
May 2000
Division of Nephrology, University and Spedali Civili, Brescia, Italy.
Background: Many attempts have been made to withdraw steroid therapy in renal transplant patients in order to avoid its many side effects. Results have been, so far, controversial. In this randomized prospective study, we compare the efficacy of azathioprine adjuncts to cyclosporine at the time of steroid withdrawal, 6 months after transplantation, versus Cyclosporine monotherapy, in preventing acute rejection.
View Article and Find Full Text PDF[Metabolic evaluation of urinary calculi. What is a reasonable limitation? 2: Practical approach].
J Urol (Paris)
November 1985
There appears to be little justification for conducting major metabolic screening for all cases of urinary calculi, both because of the cost, and the weak therapeutic advantages faced with the increased urine output. It is more logical to use simple methods to distinguish two groups of patients: Those in whom the affection is easily curable: dietary excess, abuse of therapeutic means, hyperparathyroidism, uric acid stones. Those in whom the affection may become worse: cystinuria, urinary malformations, recurrent calculi.
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