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Experience of a tertiary/quaternary unit with surgery for endocrine hypertension.
S Afr J Surg
December 2024
Department of Surgery, School of Clinical Medicine, Chris Hani Baragwanath Academic Hospital, University of the Witwatersrand, South Africa.
Background: Endocrine hypertension is believed to be underestimated worldwide especially in the developing countries. There is a scarcity of publications on endocrine hypertension in sub-Saharan Africa. The aim of this study was to reflect the profile of patients with endocrine hypertension of adrenal/paraganglioma origin at Chris Hani Baragwanath Academic Hospital (CHBAH).
View Article and Find Full Text PDFColo-colic intussusception secondary to a giant lipoma: A case report.
Radiol Case Rep
March 2025
Department of Radiology, Hôtel-Dieu de France Hospital, Saint Joseph University, Beirut, Lebanon.
Intussusception in adults is a rare condition often associated with a pathological lead point, which is frequently malignant but can occasionally be benign, such as colonic lipomas. We report the case of a 60-year-old male who presented with colicky abdominal pain, and a computed tomography (CT) revealed a colo-colic intussusception caused by a 6 cm lipoma in the transverse colon, accompanied by ischemic changes in the colonic mucosa. The patient underwent a right hemicolectomy, and histopathology confirmed the benign nature of the lesion.
View Article and Find Full Text PDFProlonged pediatric intensive care unit (PICU) admission, challenges in diagnosis and treatment in a child with hyper IgM syndrome in a tertiary hospital in Tanzania: a case report.
Pan Afr Med J
January 2025
Muhimbili National Hospital, Dar es Salaam, Tanzania.
Hyper immunoglobulin M (IgM) syndromes are a collection of uncommon primary combined immunodeficiency disorders. They are characterized by recurrent bacterial infections due to low levels of IgG, IgA, and IgE, while IgM levels remain normal or high. These conditions stem from a mutation in the CD40 ligand gene or disruptions in the CD40-signaling pathway.
View Article and Find Full Text PDFExtratesticular intrascrotal epidermoid cysts presenting like polyorchidism: a case report.
Pan Afr Med J
January 2025
Department of Surgery, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia.
Bilateral scrotal masses may present as polyorchidism or benign neoplasms. Epidermoid cysts (ECs) are common benign cutaneous lesions that are characterized by encapsulated sebaceous cysts containing keratin. These cysts can undergo complications such as ruptures, infections, or daughter cyst formation.
View Article and Find Full Text PDFPembrolizumab is a monoclonal antibody directed against the programmed cell death-1 (PD1) receptor, which binds to PD1 receptors on T lymphocytes and blocks their inactivation by tumor cells. Pembrolizumab is not free from side effects, a rare one of which is hypocorticism. Here we present a patient with pembrolizumab-induced hypocorticism manifested by a cerebrovascular event.
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