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http://dx.doi.org/10.1042/bj0720027 | DOI Listing |
Sci Rep
January 2025
Department of Gastroenterology, The First Affiliated Hospital of Xinjiang Medical University, No.137 LiYuShan Road Xinjiang Province, Urumqi, 830000, China.
Although low-dose lactulose has shown a good theoretical foundation for the treatment of ulcerative colitis (UC) in previous studies, the exact effects and mechanism remain unclear. The rats were randomly distributed into 5 groups, i.e.
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January 2025
Division of Reproductive Biology, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Tuwima 10, Olsztyn, 10-748, Poland.
An inflammatory response is related to different inflammatory mediators generated by immune and endometrial cells. The links between lipopolysaccharide (LPS), cytokines, and leukotrienes (LTs) in endometrial stromal cells remain unclear. This study aimed to examine the influence of LPS, tumor necrosis factor (TNF)-α, interleukin (IL)-1β, IL-4 and IL-10 on 5-lipooxygenase (5-LO), LTA4 hydrolase (LTAH) and LTC4 synthase (LTCS) mRNA and protein abundances, and LTB4 and cysteinyl (cys)-LTs release including LTC4, by the cultured pig endometrial stromal cells, as well as on cell viability.
View Article and Find Full Text PDFCell Death Dis
January 2025
Faculty of Medicine, Institute of Biochemistry I, Goethe University Frankfurt, Frankfurt, Germany.
Arachidonate 15-lipoxygenase type B (ALOX15B) peroxidises polyunsaturated fatty acids to their corresponding fatty acid hydroperoxides, which are subsequently reduced into hydroxy-fatty acids. A dysregulated abundance of these biological lipid mediators has been reported in the skin and blood of psoriatic compared to healthy individuals. RNAscope and immunohistochemistry revealed increased ALOX15B expression in lesional psoriasis samples.
View Article and Find Full Text PDFAnim Sci J
January 2025
General Terán Experimental Field, National Institute of Forestry, Agricultural and Livestock Research, General Terán, Mexico.
The objective of this study was to evaluate the impact of incorporating palmitic acid into the diet of dairy goats on the physicochemical characteristics, nutritional value, and fatty acid profile of goat kid meat. For this, 28 Creole local kids were used, divided into the following treatments: grazing, kids fed milk from grazing goats; base diet, kids fed milk from goats in confinement with a total mixed ration; base diet + 3PA, kids fed milk from goats in confinement that consumed the base diet plus 3% palmitic acid; and base diet + 6PA, kids fed milk from goats in confinement fed with the base diet plus 6% palmitic acid. The feeding period was conducted over a 30-day period.
View Article and Find Full Text PDFCarbohydr Polym
March 2025
Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China. Electronic address:
This study explores the effect of fatty acid chain length in regulating the structural changes and physicochemical properties of high-amylose maize starch (HAMS) induced by annealing with fatty acid solution (AFAS). AFAS was found to effectively regulate the conformation of amylose molecular chains within starch granules. Annealing with fatty acids of shorter chain length, such as lauric acid, promoted the formation of both double and single helices within HAMS granules.
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