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Idiopathic intracranial hypertension in a paediatric population: a retrospective observational study on epidemiology, symptoms and treatment.
J Biol Regul Homeost Agents
June 2017
General Paediatrics O.U., Policlinico-Vittorio Emanuele University Hospital, University of Catania, Italy.
Idiopathic intracranial hypertension (IIH) is a disorder of unknown origin, which is characterized by elevated intracranial pressure (ICP) without underlying etiological evidence of neurological disease. The purpose of the current study was to evaluate epidemiological features, clinical presentation, diagnostic findings and treatment of sixteen children (7 males and 9 females) with IIH. Medical records of the patients were obtained from the University Paediatric Hospital of Catania, Italy.
View Article and Find Full Text PDFCorneal thickness in children with growth hormone deficiency: the effect of GH treatment.
Growth Horm IGF Res
August 2014
Biomedical Department of Internal and Specialistic Medicine (DIBIMIS), Section of Endocrinology, Diabetology and Metabolism, University of Palermo, Palermo, Italy. Electronic address:
Objective: The eye represents a target site for GH action, although few data are available in patients with GH deficiency (GHD). Our aim was to evaluate central corneal thickness (CCT) and intraocular pressure (IOP) values in GHD children to assess the role played by GHD or GH treatment on these parameters.
Design: In 74 prepubertal GHD children (51M, 23F, aged 10.
Evaluation impact of long-term usage of inhaled fluticasone propionate on ocular functions in children with asthma.
Steroids
May 2011
Department of Pediatrics, Division Pediatric Allergy, Bezmialem Vakıf University Medical Faculty, Istanbul, Turkey.
Objective: Although systemic, topical, and periocular corticosteroid administration have long been associated with ocular side effects, there has been little evidence to suggest that long-term inhaled corticosteroids can cause ocular side effects. The aim of this study was to evaluate the effects of long term treatment inhaled fluticasone propionate spray usage the recommended dose on some ocular functions in pediatric patients with asthma.
Methods: The study group consisted of 266 prepubertal children with asthma who had used inhaled fluticasone propionate spray at 3-6 years intermittently.
The oestrogenized rat myometrium inhibits organotypic sympathetic reinnervation.
Auton Neurosci
October 2002
Laboratorio de Biología Celular, Instituto de Investigaciones Biológicas Clemente Estable, Avenida Italia 3318, Montevideo 11600, Uruguay.
Chronic administration of oestrogen to rats during the infantile/prepubertal period provokes, at 28 days of age, complete loss of noradrenaline-labelled intrauterine sympathetic nerves. It is not known whether oestrogen inhibits the growth or causes the degeneration of developing uterine sympathetic nerves, or whether the uterus recovers its innervation following cessation of infantile/prepubertal oestrogen treatment. In the present study, we analysed the time-course of the effects of oestrogen on the development of uterine sympathetic nerves in the rat, using histochemical methods.
View Article and Find Full Text PDFDifferential effects of oestrogen on developing and mature uterine sympathetic nerves.
Cell Tissue Res
April 2002
Laboratorio de Biología Celular, Instituto de Investigaciones Biológicas Clemente Estable, Montevideo, Uruguay.
Oestrogen is a key factor in the remodelling of uterine sympathetic nerves during puberty and the oestrous cycle; these nerves are influenced by changes in their target uterine tissue. The magnitude of oestrogen-induced responses might however be influenced by the maturation stage of sympathetic nerve fibres, the age of the neurons and/or the developmental state of the uterus. We have therefore compared the sympathetic innervation of the uterus following chronic oestrogen treatment of infantile/prepubertal and young adult intact and ovariectomised rats.
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