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Coital signaling in the female rabbit involves sequential events in the brainstem and hypothalamus, resulting in a massive release of hypothalamic gonadotropin-releasing hormone (GnRH) that peaks within 1-2 h after mating. The neural connections between coitus and GnRH release involves norepinephrine (NE) and acetylcholine (ACh) since administration of antagonists against NE (dibenamine or phentolamine) or ACh (atropine, alpha-bungarotoxin (alpha-BTX) or scopolamine) blocks or attenuates ovulating events. Moreover, hypothalamic NE release and brainstem tyrosine hydroxylase (TH, the rate-limiting enzyme for NE synthesis) expression in the noradrenergic areas increase prior to, or in concert with, the preovulatory GnRH surge.

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Physiological color change in the bullfrog, Rana catesbeiana.

J Exp Zool

February 1999

Departamento de Fisiologia, Universidade de São Paulo, Brasil.

Adults of Rana catesbeiana maintained for 4 days in 12:12 light/dark regimen exhibited a rhythmic color change of 24 hr. Under constant light, however, the rhythm disappeared, and the reflectance values gradually became greater, that is the animals became lighter. Under constant darkness, the rhythm was also abolished, but the animals tended to a darker color.

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1. A method is described for measuring continuously the efflux of potassium or rubidium from smooth muscle of the guinea-pig. 2.

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Interactions between responses mediated by activation of adenosine A2 receptors and alpha 1-adrenoceptors in the rabbit isolated aorta.

Br J Pharmacol

June 1993

Department of Pharmaceutical Sciences, College of Pharmacy and Allied Health Professions, St. John's University, Jamaica, New York 11439.

1. This paper describes aspects of the functional antagonism between the responses mediated by activated alpha 1-adrenoceptors and adenosine A2 receptors in the adventitia- and endothelium-denuded aorta of the rabbit. 2.

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To study the nature of adrenergic stimulation of ions and water reabsorption in the newt renal distal tubule, stationary microperfusion of the nephron and electron probe analysis were used. After application of norepinephrine (NE 10(-6) M) to the tubule surface, the fractional reabsorption of fluid increased from 15.0 +/- 3.

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