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Introduction: Cardiovascular disease remains a leading cause of morbidity and mortality worldwide, with many individuals presenting with acute ischemic stroke or transient ischemic attack (AIS/TIA) due to underlying vascular risk factors (VRF). While these patients typically undergo routine evaluations for acute treatment, the prevention of these conditions is often underestimated. This study reports the prevalence of non-optimized VRF and estimates their degree of avoidability in a cohort of patients treated in a tertiary care center following AIS/TIA.

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Background: Utilization of oral anticoagulants for acute ischemic stroke (AIS) prevention in patients with atrial fibrillation (AF) increased in the United States over the last decade. Whether this increase has been accompanied by any change in AF prevalence in AIS at the population level remains unknown. The aim of this study is to evaluate trends in AF prevalence in AIS hospitalizations in various age, sex, and racial subgroups over the last decade.

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Transesophageal echocardiogram in the evaluation of acute ischemic stroke of young adults.

Brain Circ

May 2021

Department of Neurological Surgery, Division of Endovascular Neurosurgery, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

Introduction: Acute ischemic stroke (AIS) in the young age (≤50 years) is a major cause of disability. The underlying mechanism of AIS in this age group is usually different from elderly. Transthoracic echocardiography (TTE) is used to detect the potential cardiac sources of embolism in AIS patients.

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Rationale: About one-third of ischaemic strokes are caused by cardioembolism, and a substantial proportion of cryptogenic strokes likely also originate from the heart or aortic arch. Early determination of aetiology is important to optimise management. Computed Tomography-angiography of the heart is emerging as an alternative to echocardiography to detect cardio-aortic sources of embolism in stroke patients, but its diagnostic yield in acute ischaemic stroke has not been thoroughly assessed.

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Determinants of preventable stroke-Ankara ACROSS stroke preventability study.

J Stroke Cerebrovasc Dis

July 2020

Department of Neurology, Faculty of Medicine, Hacettepe University, Sihhiye, 06100 Ankara, Turkey. Electronic address:

Article Synopsis
  • Unhealthy lifestyles and poorly managed vascular risk factors significantly contribute to stroke incidents and outcomes.
  • A study of 787 ischemic stroke patients showed that nearly 49% had four or more modifiable risk factors that could have been optimized to prevent strokes.
  • Key predictors for preventable strokes included younger age, female gender, and certain types of artery issues, highlighting the need for targeted strategies in risk factor management.
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