[The significance of the content of connective tissue metabolites in the blood serum for the diagnosis of chronic viral hepatitis and liver cirrhosis].

With the purpose of improving early clinico-biochemical diagnosis of viral chronic active hepatitis and liver cirrhosis in children, the authors used indices of connective tissue metabolism--determination of free oxiprolin and neutral lipids in the blood serum. High levels of free oxiprolin and neutral lipids were revealed in patients with chronic active hepatitis and low--in liver cirrhosis. These data characterize different reactions of the connective tissue in the named diseases determined by different morphological maturity grades and secretory activity of fibroblasts.