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[Focus on the outbreaks of invasive group A streptococcal disease].
Zhonghua Yi Xue Za Zhi
January 2025
Key Laboratory of Major Diseases in Children, Ministry of Education, National Clinical Research Center for Respiratory Diseases, National Key Discipline of Pediatrics, Laboratory of Infection and Microbiology, Beijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing100045, China.
In recent years, particularly since the outbreaks of scarlet fever and invasive group A streptococcal diseases/infections (iGAS) in several European countries in 2022, iGAS has garnered widespread attention. Recently, Japan experienced an outbreak of a specific type of iGAS, streptococcal toxic shock syndrome (STSS). The outbreak was reported under the label"flesh-eating bacteria,"emphasizing the pathogenic potential of group A streptococcus (GAS).
View Article and Find Full Text PDFCharacterization of a novel SNP identified in Australian group A isolates derived from the M1 lineage.
mBio
December 2024
Institute for Molecular Bioscience, Australian Infectious Diseases Research Centre, The University of Queensland, Brisbane, Queensland, Australia.
Group A (GAS) is a human-adapted pathogen responsible for a variety of diseases. The GAS M1 lineage has contributed significantly to the recently reported increases in scarlet fever and invasive infections. However, the basis for its evolutionary success is not yet fully understood.
View Article and Find Full Text PDFAlveolar Bone Actinomycosis Affecting a Pediatric Patient: Diagnosis and Conservative Management.
Indian J Otolaryngol Head Neck Surg
October 2024
Oral Pathology, Department of Stomatology, Public Oral Health, and Forensic Dentistry, Ribeirão Preto Dental School (FORP/USP), University of São Paulo, Av Do Café, S/n Campus USP, Ribeirão Preto, São Paulo, Ribeirão Preto, Brazil.
Article Synopsis
- Actinomycosis is a rare infection caused by certain types of gram-positive bacteria, primarily affecting soft and bone tissues, and occurs in about 3% of cases in children.
- A case involving a 4-year-old girl showed an extensive ulcerative lesion in the maxilla, which developed after a prior diagnosis of scarlet fever and led to damage in surrounding tissues.
- Successful treatment involved surgical removal of affected bone and teeth, followed by local treatment, highlighting the need for pediatric dentists to recognize actinomycosis and its implications for diagnosis and care.
Epidemiology of scarlet fever in Victoria, Australia, 2007-2017.
Epidemiol Infect
October 2024
The Royal Melbourne Hospital, Melbourne, VIC, Australia.
Article Synopsis
- * Out of 1,578 cases recorded, the majority were seen in children under 10 years old, with 24% requiring hospitalization; there were no reported deaths.
- * The annual incidence rate was stable at an average of 2.5 cases per 100,000, with higher rates among children under 5 and boys, but the discovery of a new variant raises concerns about potential future outbreaks.
Maud L. Menten: Pioneering Physician and Biochemist.
Cureus
August 2024
Internal Medicine, Wellstar Health System, Marietta, USA.
Article Synopsis
- Dr. Maud Leanora Menten was a pioneering Canadian physician and biochemist who made significant contributions to various fields of biochemistry for over 40 years, particularly in cancer treatments and enzyme kinetics.
- She was a trailblazer for women in science, being among the first in Canada to earn both an MD and a PhD, and after facing restrictions, she published around 100 research studies, notably collaborating with Dr. Leonor Michaelis on the famous Michaelis-Menten equation.
- Although her contributions in hemoglobin research were overshadowed by Linus Pauling, her legacy gained recognition posthumously, with honors from the University of Toronto and the Canadian Medical Hall of Fame.
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