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Cureus
December 2024
Department of Cardiology, Japanese Red Cross Maebashi Hospital, Maebashi, JPN.
When encountering severe hypoxemia that does not respond to oxygen supplementation, it is essential to consider underlying right-to-left shunting. Among various diagnostic approaches, the microbubble test via transthoracic echocardiography (TTE) is a simple, noninvasive method for detecting pulmonary arteriovenous shunts, particularly in hepatopulmonary syndrome (HPS). Although microbubbles are usually administered peripherally, using a Swan-Ganz (SG) catheter to inject microbubbles directly into the pulmonary artery may provide even more definitive diagnostic information.
View Article and Find Full Text PDFLeg Med (Tokyo)
December 2024
Department of Forensic Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan.
Using human cardiac blood from forensic autopsy cases, comprehensive measurements of albumin, vitamins A, B1, B6, B12, C, D, folate, and PIVKA-Ⅱ were performed. Of 128 cases, 83 were male, with an average age of 61.8 years and average postmortem interval of 44 h.
View Article and Find Full Text PDFCrit Care Explor
December 2024
Section of Pediatric Critical Care, Department of Pediatrics, Cumming School of Medicine, University of Calgary, Alberta Children's Hospital, Calgary, AB, Canada.
Background: Acute illness states with increased metabolic demand can precipitate severe thiamine deficiency if physiologic needs exceed endogenous stores and supplementation. Patients with preexisting risk factors such as parenteral nutrition (PN) dependence, eating disorders, gastrointestinal disorders, or surgeries are especially vulnerable.
Case Summary: A 9-year-old girl with short bowel syndrome receiving long-term PN, including standard thiamine supplementation, presented with refractory shock following aspiration.
J Clin Biochem Nutr
November 2024
Research Support Center, Shizuoka General Hospital, 4-27-1 Kita-Ando, Aoi, Shizuoka 420-8527, Japan.
Heart failure is a major manifestation of vitamin B deficiency; beriberi. We have previously reported that even vitamin B insufficiency, milder than deficiency, is a risk for heart failure in the institutionalized elderly. Then in this cross-sectional study, sixty-eight cardiology outpatients were evaluated for their whole blood vitamin B and plasma brain natriuretic peptide (BNP) concentrations, a sensitive marker of heart failure, as well as their dietary intake.
View Article and Find Full Text PDFCureus
August 2024
Department of Cardiology, National Hospital Organization Hiroshima-Nishi Medical Center, Otake, JPN.
Thiamine deficiency can cause various clinical manifestations. Wet beriberi, a phenotype of thiamine deficiency, is often underdiagnosed in clinical practice due to the nonspecificity of symptoms. An 83-year-old man presented to a primary care clinic with a two-month history of progressing edema in the scrotum and lower extremities.
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