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Is Membrane Filtration Applicable for the Recovery of Biologically Active Substances from Spent Lavender?
Membranes (Basel)
January 2025
Department of Chemical Engineering, University of Chemical Technology and Metallurgy, 1576 Sofia, Bulgaria.
This study explored the batch membrane filtration of 40% ethanol extracts from spent lavender, containing valuable compounds like rosmarinic acid, caffeic acid, and luteolin, using a polyamide-urea thin film composite X201 membrane. Conducted at room temperature and 20 bar transmembrane pressure, the process demonstrated high efficiency, with rejection rates exceeding 98% for global antioxidant activity and 93-100% for absolute concentrations of the target components. During concentration, the permeate flux declined from 2.
View Article and Find Full Text PDFThe Underutilization of Urea in the Treatment of SIADH - An Efficacious but Overlooked Solution.
Cureus
November 2024
Anaesthesia, Dow Health Sciences Karachi, Karachi, PAK.
The syndrome of inappropriate antidiuretic hormone secretion (SIADH) is a frequent cause of hyponatremia that presents substantial management challenges in clinical settings. Despite a range of treatment options, including fluid restriction, demeclocycline, and vasopressin antagonists, urea remains underutilized, particularly in North America, despite its well-documented efficacy, safety, and cost-effectiveness. Urea corrects hyponatremia by promoting osmotic diuresis without causing significant fluid shifts, making it an ideal treatment for both acute and chronic SIADH.
View Article and Find Full Text PDFHyperosmolality activates polycystin-2 and TRPM4 in renal primary cilium.
Pflugers Arch
December 2024
Department of Pharmacology, Physiology, and Neurobiology, University of Cincinnati, Cincinnati, OH, USA.
Article Synopsis
- Autosomal dominant polycystic kidney disease (ADPKD) features the development of renal cysts due to mutations in proteins found in renal epithelial cell cilia, particularly polycystin-2 (PC2), an ion channel.
- Recent research shows that urine activates a significant cation-conducting current in these cilia, unlike previous studies that used standard solutions.
- External hyperosmolality, induced by substances like urea, enhances the activity of TRPM4 channels and the ciliary PC2 channels, suggesting a connection between ion channel activity and cyst formation.
Long-Term Persistence of Inappropriate Antidiuretic Hormone Secretion Following Minor Head Injury.
Eur J Case Rep Intern Med
November 2024
Department of Internal Medicine, Iris Hospitals South (Molière), Brussels, Belgium.
Unlabelled: The syndrome of inappropriate antidiuretic hormone secretion (SIADH) is a common cause of euvolemic hyponatremia, resulting from non-osmotic release of antidiuretic hormone (ADH). SIADH is frequently associated with neurological conditions, including traumatic brain injury (TBI). TBI-associated SIADH usually develops within days to weeks and resolves within a few weeks.
View Article and Find Full Text PDFDiethyl aminoethyl hexanoate ameliorates salt tolerance associated with ion transport, osmotic adjustment, and metabolite reprograming in white clover.
BMC Plant Biol
October 2024
College of Grassland Science and Technology, Sichuan Agricultural University, Chengdu, 611130, China.
Background: Soil salinization is a serious environmental hazard, limiting plant growth and production in different agro-ecological zones worldwide. Diethyl aminoethyl hexanoate (DA-6) as an essential plant growth regulator (PGR) exhibits a beneficial role in improving crop growth and stress tolerance. However, the DA-6-regulated effect and mechanism of salt tolerance in plants are still not fully understood.
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