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Anti-MAG neuropathy: historical aspects, clinical-pathological correlations, and considerations for future therapeutical trials.
Arq Neuropsiquiatr
June 2024
Universidade Federal do Ceará, Departamento de Medicina Clínica, Serviço de Neurologia, Fortaleza CE, Brazil.
Background: Patients with anti-MAG neuropathy present with distal demyelinating polyneuropathy, IgM monoclonal gammopathy, and elevated titers of anti-MAG antibodies.
Objective: This paper reviews what is known about the clinical presentation, course, pathophysiology, and treatment of anti-MAG neuropathy, with considerations for the design of therapeutic trials.
Methods: A literature review of the medical and scientific literature related to anti-MAG neuropathy, and the design of therapeutic clinical trials in peripheral neuropathy.
The circle of reentry: Characteristics of trigger-substrate interaction leading to sudden cardiac arrest.
Front Cardiovasc Med
April 2023
Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, Netherlands.
Sudden cardiac death is often caused by ventricular arrhythmias driven by reentry. Comprehensive characterization of the potential triggers and substrate in survivors of sudden cardiac arrest has provided insights into the trigger-substrate interaction leading to reentry. Previously, a "Triangle of Arrhythmogenesis", reflecting interactions between substrate, trigger and modulating factors, has been proposed to reason about arrhythmia initiation.
View Article and Find Full Text PDFPostpartum Guillain-Barré syndrome: a case report.
Ann Med Surg (Lond)
February 2023
Department of General Practice and Emergency Medicine, Dharan, Sunsari, Nepal.
Unlabelled: Guillain-Barré syndrome (GBS) is an immune-mediated disorder of the central nervous system presenting as symmetrical, progressive weakness and areflexia. The incidence of GBS is very low during pregnancy, but the risk increases in the postpartum period. The management is done by intravenous immunoglobulin or conservatively.
View Article and Find Full Text PDFClinical predictors and electrodiagnostic characteristics in patients with Guillain-Barré syndrome with respiratory failure: a retrospective, matched case-control study.
PeerJ
January 2023
Department of Rehabilitation Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Background: Respiratory failure is a common complication of Guillain-Barré syndrome (GBS). This study aimed to determine the clinical predictors and electrodiagnostic (EDx) characteristics in patients with Guillain-Barré syndrome (GBS) with respiratory failure.
Methods: The retrospective study included 29 confirmed GBS cases with respiratory failure and age- (±5 years) and sex-matched controls (1:1).
Emergence of F-waves after repetitive nerve stimulation.
Clin Neurophysiol Pract
May 2020
LA Neuromuscular Center, 8750 Wilshire Blvd Ste 350, Beverly Hills, CA 90211, USA.
Aim: Absence of the F-wave may represent the inability of spinal motor neurons to be excited after periods of inactivity. Repetitive stimulation in an otherwise immobile patient acts as a voluntary movement therefore allowing for the production of an F-wave in a patient with previously demonstrated absent F-waves. Through this case report, we attempt to highlight that the absence of the F-wave may result from inexcitability of spinal motor neurons after reduced mobilization.
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