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Effects of in vitro simulated digestion on the hypoglycaemic capacity of wheat bran-soluble dietary fibre.
Biochem Biophys Res Commun
December 2024
College of Food Science and Engineering, Nanjing University of Finance and Economics, Nanjing, 210023, China. Electronic address:
Wheat bran-soluble dietary fibre (WB-SDF) is known for its hypoglycaemic properties and its potential to control postprandial blood glucose levels in individuals with hyperglycaemia. However, the digestive process may alter its glucose-lowering potential. This study investigated the effects of in vitro simulated digestion on the hypoglycaemic efficacy of WB-SDF.
View Article and Find Full Text PDFDesign, Synthesis, and Biological Activity Evaluation of 5-Aryl-cyclopenta[]pyridine Derivatives.
J Agric Food Chem
January 2025
Institute of Applied Chemistry, Jiangxi Academy of Sciences, Nanchang 330096, China.
Taking the natural product cerbinal as the lead compound, 30 novel 5-aryl-cyclopenta[]pyridine derivatives were designed and synthesized based on the previous bioactivity studies of the cyclopenta[]pyridines. The modification of the position-5 of compound was achieved by amination, bromination, and cross coupling using cerbinal as the raw material. The results of the bioactivity tests demonstrated that partial compounds exhibited superior activity against plant viruses compared to compound .
View Article and Find Full Text PDFIntratracheal instillation for the testing of pulmonary toxicity in mice-Effects of instillation devices and feed type on inflammation.
Animal Model Exp Med
January 2025
National Research Centre for the Working Environment, Copenhagen, Denmark.
Background: Inhalation exposure is the gold standard when assessing pulmonary toxicity. However, it typically requires substantial amounts of test material. Intratracheal instillation is an alternative administration technique, where the test substance is suspended in a liquid vehicle and deposited into the lung via the trachea.
View Article and Find Full Text PDFThe relationship between kidney function and cardiometabolic risk factors, anthropometric indices, and dietary inflammatory index in the Iranian general population: a cross-sectional study.
BMC Nephrol
January 2025
Nutrition Research Center, Department of Clinical Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.
Background: The prevalence of chronic kidney disease (CKD) is estimated to be about 13.4% worldwide. Studies have shown that CKD accounts for up to 2% of the health cost burden.
View Article and Find Full Text PDFProviding medically tailored groceries and food resource coaching through the charitable food system to patients of a safety-net clinic in Dallas, Texas: a randomised controlled trial protocol.
BMJ Open
January 2025
O'Donnell School of Public Health, UT Southwestern Medical Center, Dallas, Texas, USA
Introduction: Linking patients living with chronic, diet-related diseases and food insecurity to charitable food assistance, medically tailored groceries (MTGs) and food resource coaching may empower patients to better manage their health in a way that is economically sustainable. This protocol paper describes the implementation of a study evaluating MTGs and food resource coaching in a food pantry setting.
Methods And Analysis: A randomised controlled trial whereby patients of a safety-net health centre will be screened for The Emergency Food Assistance Program (TEFAP) and study eligibility.
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