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Imported Systemic Endemic Mycoses in Spain 1997-2021: An Analysis of a National Hospital Database.
Mycoses
January 2025
Clinical Medicine Department, Miguel Hernández University, Elche, Spain.
Background: Systemic endemic mycoses are systemic fungal infections typically found in tropical and subtropical regions. Their global incidence is rising, including in nonendemic countries, mainly due to migration and international travel. They are a major cause of morbidity and mortality worldwide, especially in immunocompromised patients.
View Article and Find Full Text PDFChallenging granulomatous differential diagnosis of CNS lesions in a 75-year-old patient with indolent lymphoma.
Front Immunol
December 2024
Department of Internal Medicine I, Saarland University Medical School, Homburg/Saar, Germany.
We report here on a patient with concomitant indolent lymphoma who showed a rapid progressive deterioration of his general condition and emerging neurological symptoms. The combination of severe B symptoms with hypermetabolic involvement of the adrenal glands and multiple central nervous system (CNS) lesions initially suggested a malignant disease. However, when the patient presented to us with biopsy results from one of the CNS lesions, the biopsy revealed granulomatous inflammation but no evidence of malignancy.
View Article and Find Full Text PDFExperiences and perspectives on rapid-test diagnosis of tuberculosis, histoplasmosis and cryptococcosis in people with advanced HIV/AIDS disease in Porto Alegre, Brazil.
PLoS One
November 2024
Federal University of Health Sciences of Porto Alegre (UFCSPA), Porto Alegre, Rio Grande do Sul, Brazil.
The rapid diagnosis of opportunistic infections (OIs) is critical for improving the health outcomes of people living with HIV/AIDS (PLWHA). This study aimed to describe the feasibility of implementing a package for the rapid diagnosis of tuberculosis, histoplasmosis, and cryptococcosis in patients with advanced HIV/AIDS disease in Porto Alegre, Brazil. The research involved two focus groups with health professionals, four in-depth interviews with healthcare managers, and twelve interviews with PLWHA.
View Article and Find Full Text PDFPrevalence of Opportunistic Infections in Treatment-Naive HIV Patients in a Secondary Care Center.
Cureus
November 2024
General Medicine, Hospital General Atlántida, La Ceiba, HND.
Article Synopsis
- HIV-related immunosuppression raises the risk of opportunistic infections (OIs) among patients, and a study in Honduras assessed the prevalence of these OIs in individuals who haven't received antiretroviral therapy (ART).
- The study found that out of 110 treatment-naive HIV patients, 28.2% had OIs, with the most common being cryptococcosis, candidiasis, and tuberculosis.
- The findings highlight a concerning rise in fungal OIs and indicate the need for better resource allocation for diagnosis and treatment in the Honduran healthcare system.
Nomenclature for human and animal fungal pathogens and diseases: a proposal for standardized terminology.
J Clin Microbiol
December 2024
Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Article Synopsis
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