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Diagnostic Value of Serum miR-499a-5p in Chinese Children with Autism Spectrum Disorders.

J Mol Neurosci

January 2025

Department II of Acupuncture and Moxibustion, Dongzhimen Hospital Beijing University of Chinese Medicine, No. 116, Cuiping West Road, Tongzhou District, Beijing, 101121, China.

The purpose of this study was to investigate the expression of miR-499a-5p in children with autism spectrum disorders (ASD) and its value in early diagnosis of ASD. This is a retrospective case-control study that included 40 children with ASD as a case group and 43 healthy children as a control group. Magnetic resonance imaging (MRI) was performed on all subjects, and the children were scored with childhood autism rating scale (CARS) and autism behavior checklist (ABC).

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This study examines heat transfer and nanofluid-enhanced blood flow behaviour in stenotic arteries under inflammatory conditions, addressing critical challenges in cardiovascular health. The blood, treated as a Newtonian fluid, is augmented with gold nanoparticles to improve thermal conductivity and support drug delivery applications. A hybrid methodology combining finite element method (FEM) for numerical modelling and artificial neural networks (ANN) for stability prediction provides a robust analytical framework.

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Background: It was controversial to use open surgery or minimally invasive surgery (MIS) for adrenocortical carcinoma (ACC). This retrospective study aimed to evaluate the impact on prognosis between MIS and open surgery in patients with clinical stage I-II ACC.

Methods: Patients with stage I-II ACC from December 2000 to October 2022 were retrospectively studied.

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Background And Purpose: Prolonged length of stay (LOS) following a stroke is associated with unfavorable clinical outcomes. Factors predicting LOS in medium vessel occlusion (MeVO), impacting up to 40% of acute ischemic stroke (AIS) cases, remain underexplored. This study aims to investigate the predictors of LOS in AIS-MeVO.

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