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Phoenix Comprehensive Assessment of Pectus Excavatum Symptoms (PCAPES).
J Thorac Dis
December 2024
Department of Cardiovascular and Thoracic Surgery, Mayo Clinic, Phoenix, AZ, USA.
Background: Pectus excavatum (PE) can cause cardiopulmonary compression with a wide range of symptoms and psychosocial effects. Few validated surveys assess the extensive symptomatology of the adult pectus population. A comprehensive symptom survey was developed and validated with outcomes presented.
View Article and Find Full Text PDFPancreatic Cancer: The Advanced Practitioner's Role in Early Diagnosis and Management.
J Adv Pract Oncol
November 2024
From Carson Newman University and Tennessee Cancer Specialists, Powell, Tennessee.
Pancreatic cancer is one of the most fatal cancers in the United States. Currently, it is the third leading cause of cancer-related deaths, and it is estimated that by 2030, it will be the second leading cause of cancer-related deaths behind lung cancer. It has poor overall survival rates, even with aggressive treatment.
View Article and Find Full Text PDFBorderline Personality Disorder Symptoms and Stressful Life Events: An Evaluation of Gene-Environment Interplay.
Biol Psychiatry Glob Open Sci
November 2024
PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.
Background: Borderline personality disorder (BPD) is associated with high rates of stressful life events (SLEs). It is unclear whether people who experience SLEs have more BPD symptoms after accounting for the effects of familial risk factors. Our aims in the current study were to 1) create a predictive model of BPD using stressors across age and contexts and 2) examine whether SLEs resulted in higher levels of BPD symptoms beyond the effects of genetic and environmental risk factors.
View Article and Find Full Text PDFThe lymphocele conundrum: incidence and management in early renal transplants.
J Pak Med Assoc
January 2025
Department of Urology, Sindh Institute of Urology and Transplantation, Karachi, Pakistan.
Objective: To assess the incidence of post-transplant lymphocele, identify risk factors, and analyse the effectiveness and outcomes of different management approaches.
Methods: The prospective, descriptive study was conducted at the Department of Renal Transplant, Sindh Institute of Urology and Transplantation, Karachi, from February 25, 2021, to December 25, 2022, and comprised of 300 transplant. Ultrasound was performed in all patients presenting with symptomatology attributed to lymphocele.
Perhexiline-induced toxicity in a geriatric patient presenting with peripheral neuropathy, hepatotoxicity and recurrent falls.
BMJ Case Rep
January 2025
Austin Health, Heidelberg, Victoria, Australia.
Perhexiline is an antianginal medication used in refractory disease. Despite being highly efficacious, it is seldom prescribed due to its risk of neurotoxicity and hepatotoxicity. These adverse effects are often linked to high plasma concentration in patients with impaired metabolism, identified through therapeutic drug monitoring.
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