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Article Synopsis
  • This review analyzed sedation techniques for children aged 0-8 during MRI procedures, focusing specifically on needle-free methods.
  • A total of 67 studies with over 22,000 participants were reviewed, revealing varying success rates for different sedation methods.
  • Success rates ranged from 36% for rectal, oral, or intranasal midazolam to 99% for oral pentobarbital, highlighting significant differences in effectiveness among the sedation techniques used.
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Chloral hydrate as a sedating agent for neurodiagnostic procedures in children.

Cochrane Database Syst Rev

August 2021

School of Medicine, Taylor's University, Subang Jaya, Selangor, Malaysia.

Background: This is an updated version of a Cochrane Review published in 2017. Paediatric neurodiagnostic investigations, including brain neuroimaging and electroencephalography (EEG), play an important role in the assessment of neurodevelopmental disorders. The use of an appropriate sedative agent is important to ensure the successful completion of the neurodiagnostic procedures, particularly in children, who are usually unable to remain still throughout the procedure.

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Sevoflurane is a volatile anesthetic agent that has become popular in the field of large animal anesthesia. The aim of this study was to evaluate the use of sevoflurane in adult healthy donkeys. Six male, adult, healthy donkeys were premedicated with xylazine (1 mg/kg IV), induced with thiopental (5 mg/kg IV), and then maintained for 90 minutes with sevoflurane in 100% oxygen at a flow rate of 6 L/min with spontaneous breathing.

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Background: In order to determine whether a combination of guaiphenesin, ketamine and xylazine can induce safe and satisfactory anaesthesia in mules undergoing field castration, eight healthy adult intact male mules were employed. They were premedicated with intravenous (IV) xylazine (1.3 mg/kg); an additional dose of xylazine (0.

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Management protocols for status epilepticus in the pediatric emergency room: systematic review article.

J Pediatr (Rio J)

January 2018

Boston Children's Hospital, Department of Anesthesiology, Perioperative and Pain Medicine, Division of Critical Care Medicine, Boston, United States; Boston Children's Hospital, Department of Neurology, Boston, United States.

Objective: This systematic review of national or regional guidelines published in English aimed to better understand variance in pre-hospital and emergency department treatment of status epilepticus.

Sources: Systematic search of national or regional guidelines (January 2000 to February 2017) contained within PubMed and Google Scholar databases, and article reference lists. The search keywords were status epilepticus, prolonged seizure, treatment, and guideline.

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