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Prehabilitation approaches for gastrointestinal cancer surgery: a narrative review.
Rep Pract Oncol Radiother
December 2024
Department of Medicine, Academy of Applied Medical and Social Sciences (AMiSNS), Elblag, Poland.
Gastrointestinal (GI) cancer patients undergoing surgery are particularly vulnerable to malnutrition, which can significantly impact surgical outcomes. Prehabilitation interventions encompassing nutritional, physical, and psychosocial support have gained attention for their potential to mitigate these risks. However, the efficacy of multidisciplinary prehabilitation programs in this context remains underexplored.
View Article and Find Full Text PDFGestational Oxidative Stress and OGTT: Are Pregnant Women's Fears Justified?
Diabetes Metab Syndr Obes
December 2024
Department of Medical Genetics, Aksaray University Faculty of Medicine, Aksaray, Turkey.
Purpose: Pregnancy induces significant metabolic, immunological, and endocrinological changes to support fetal growth. The 75-gram oral glucose tolerance test (OGTT) is standard for gestational diabetes screening, but concerns exist about its potential to induce oxidative stress, affecting both maternal and fetal health. The aim of the study is examining changes in oxidative stress markers and thiol/disulfide homeostasis in pregnant women to evaluate these concerns.
View Article and Find Full Text PDFAtaxia telangiectasia.
Semin Pediatr Neurol
December 2024
UPMC Children's Hospital of Pittsburgh, University of Pittsburgh, 4401 Penn Avenue, Pittsburgh, PA, 15224, USA. Electronic address:
Article Synopsis
- Ataxia telangiectasia (AT) is a rare genetic disorder caused by mutations in the ATM gene, leading to early childhood movement issues and skin changes as children grow.
- Besides neurologic symptoms, AT also affects the immune system, can increase cancer risk, and may impact respiratory and endocrine functions.
- The article discusses the role of the ATM gene, the diverse complications of AT, conditions that can resemble AT, and ongoing research for potential treatments.
Circulating RBP4 and FABP4 concentrations in patients with chronic schizophrenia are associated with increased epicardial adipose tissue volume and metabolic syndrome.
Eur Arch Psychiatry Clin Neurosci
November 2024
Division of Cardiology, Department of Internal Medicine, Taipei Veterans General Hospital, Yuli Branch, No. 91, Xinxing St., Yuli Township, Hualien, 981002, Taiwan.
Schizophrenia has been linked to an elevated cardiovascular risk profile and premature onset of cardiovascular disease. Quantifying epicardial adipose tissue (EAT) volume provides insight into its correlation with coronary artery disease (CAD) severity and associated risk factors. Previous research indicates higher pericardial adipose tissue in individuals with schizophrenia compared to non-schizophrenic counterparts.
View Article and Find Full Text PDF[Endocrinological Effects of Lithium: Pathophysiological Mechanisms and Clinical Implications].
Rev Med Chil
April 2024
Departamento de Endocrinología, Pontificia Universidad Católica de Chile, Santiago, Chile.
Lithium carbonate has a narrow therapeutic range capable of producing various adverse effects; despite this fact, it is used as first-line therapy in patients with bipolar disorder (BD) thanks to its high effectiveness. Among its adverse events are several conditions at the endocrine level, such as hypothyroidism, hyperthyroidism, hypercalcemia, hyperparathyroidism, and nephrogenic diabetes insipidus. The adherence to current guidelines for monitoring those events is low.
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